Synopsis
The problem of Protein Structure Prediction (PSP) is one of the principal topics in Bioinformatics. Multiple approaches have been developed in order to predict the protein structure of a protein. Determining the three dimensional structure of proteins is necessary to understand the functions of molecular protein level. An useful, and commonly used, representation for protein 3D structure is the protein contact map, which represents binary proximities (contact or non-contact) between each pair of amino acids of a protein. This book includes a compilation of the soft computing techniques for the protein structure prediction problem (secondary and tertiary structures). Two novel evolutionary structure predictors are also described in this work: a multi-objective evolutionary approach for contact map prediction and an evolutionary secondary structure predictor. Both of them are based on physico-chemical properties of amino acids. The evolutionary algorithms produce a set of decision rules that identifies contacts between amino acids and secondary structure motifs, respectively. Results obtained confirm the validity of our proposals.
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About the Author
Dr. Alfonso E. Márquez Chamorro received the degree and the MS degree in Computer Science from the Autónoma University of Madrid, in 2007 and 2009. In 2013, he obtained his PhD degree in Biotechnology from the Pablo de Olavide University of Seville. His research interests focus mainly on Machine Learning and Data Mining applied to Bioinformatics.
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Protein Structure Prediction based on Evolutionary Methods
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The problem of Protein Structure Prediction (PSP) is one of the principal topics in Bioinformatics. Multiple approaches have been developed in order to predict the protein structure of a protein. Determining the three dimensional structure of proteins is necessary to understand the functions of molecular protein level. An useful, and commonly used, representation for protein 3D structure is the protein contact map, which represents binary proximities (contact or non-contact) between each pair of amino acids of a protein. This book includes a compilation of the soft computing techniques for the protein structure prediction problem (secondary and tertiary structures). Two novel evolutionary structure predictors are also described in this work: a multi-objective evolutionary approach for contact map prediction and an evolutionary secondary structure predictor. Both of them are based on physico-chemical properties of amino acids. The evolutionary algorithms produce a set of decision rules that identifies contacts between amino acids and secondary structure motifs, respectively. Results obtained confirm the validity of our proposals. 204 pp. Englisch. Seller Inventory # 9783659393488
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Taschenbuch. Condition: Neu. Protein Structure Prediction based on Evolutionary Methods | Alfonso E. Márquez Chamorro | Taschenbuch | 204 S. | Englisch | 2013 | LAP LAMBERT Academic Publishing | EAN 9783659393488 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu. Seller Inventory # 105922401
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The problem of Protein Structure Prediction (PSP) is one of the principal topics in Bioinformatics. Multiple approaches have been developed in order to predict the protein structure of a protein. Determining the three dimensional structure of proteins is necessary to understand the functions of molecular protein level. An useful, and commonly used, representation for protein 3D structure is the protein contact map, which represents binary proximities (contact or non-contact) between each pair of amino acids of a protein. This book includes a compilation of the soft computing techniques for the protein structure prediction problem (secondary and tertiary structures). Two novel evolutionary structure predictors are also described in this work: a multi-objective evolutionary approach for contact map prediction and an evolutionary secondary structure predictor. Both of them are based on physico-chemical properties of amino acids. The evolutionary algorithms produce a set of decision rules that identifies contacts between amino acids and secondary structure motifs, respectively. Results obtained confirm the validity of our proposals.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 204 pp. Englisch. Seller Inventory # 9783659393488
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