Complement Receptor Type 1 Expression and Genotype Relationships: Distribution of Density and Knops Blood Group Polymorphisms of Complement Receptor 1 in Normal Healthy Indian Subjects - Softcover

Kumar, Ajay

Softcover

ISBN 10: 3659375292 ISBN 13: 9783659375293

Publisher: LAP LAMBERT Academic Publishing, 2013

Synopsis

This book incorporates the studies on direct effect of a particular genotype on the E-CR1 levels and Knops Blood Group Polymorphism. Complement receptor 1 (CR1, CD35, C3b/C4b receptor) is an immune regulatory molecule that is expressed on the surface of erythrocytes (RBCs), macrophages, neutrophils, lymphocytes, follicular dendritic cells and kidney podocytes. The functions of CR1 are binding to and removal of C4b and C3b bearing immune complexes from the circulation, enhancement of phagocytosis, regulation of complement activation by means of decay-accelerating activity for C3 convertases and cofactor activity for factor I, and serves as a complement regulatory protein. This book is for undergraduate and postgraduate students of Biochemistry and Immunology. It provides background theory of complement system and distribution of density and knops blood group polymorphisms of complement receptor 1 in normal healthy Indian subjects.

About this title

About the Author

Ajay Kumar is working as Assistant Professor, Department of Biotechnology, Lovely Professional University, Punjab, India. He obtained his post graduation degree from University School of Biotechnology, GGS Indraprastha University, New Delhi, India. He has over six years of experience in teaching postgraduate students of engineering and science.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2013
• Language: English
• ISBN 10: 3659375292
• ISBN 13: 9783659375293
• Binding: Paperback
• Number of pages: 56