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Synopsis
Conventional oral dosage forms provide a specific drug concentration in the systemic circulation without offering any control over the rate of drug delivery. Controlled-release drug delivery systems (CRDDS) provide drug release at a predetermined, predictable, and controlled rate. It was attempt to develop a gastro retentive drug delivery system of anti hypertensive drug using different polymers like that HPMCK4M, Xanthangum, PolyoxWSR303as matrixing agent, swelling agent, respectivel. A simplex lattice design was applied to combined effect of three formulation variables (ie, amount of HPMCK4M (X1), xanthangum (X2), and PolyoxWSR303 (X3). Results of multiple regression analysis indicated that low level of X1 and X 2 and high level of X3 should be used to manufacture the tablet formulation with desired in % swelling index and % drug release profile . When Polyox 303 was used, % swelling index increased, with increase on the total amount of drug released. Decreasing the amount of HPMC K4M while maintaining the total amount of polymer constant increased the release rate and total amount released. Decreasing the total amount of polymer decreases the swelling and work of penetration,
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About the Author
Prof. Ravi Patel is working as head and Assistant Professor, Dept of Pharmaceutics and Prof. Jitendra Bhangale is working as head and Assistant Professor, Dept of Pharmacology at Shree Saurashtra Patel Sewa Samaj's Smt. N. M. Padalia Pharmacy College, Ahmedabad, Gujarat, 382210 India.
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Anti Hypertensive drug- Formulation and its characterization
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LAP LAMBERT Academic Publishing Feb 2013, 2013
ISBN 10: 3659355208
ISBN 13: 9783659355202
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Conventional oral dosage forms provide a specific drug concentration in the systemic circulation without offering any control over the rate of drug delivery. Controlled-release drug delivery systems (CRDDS) provide drug release at a predetermined, predictable, and controlled rate. It was attempt to develop a gastro retentive drug delivery system of anti hypertensive drug using different polymers like that HPMCK4M, Xanthangum, PolyoxWSR303as matrixing agent, swelling agent, respectivel. A simplex lattice design was applied to combined effect of three formulation variables (ie, amount of HPMCK4M (X1), xanthangum (X2), and PolyoxWSR303 (X3). Results of multiple regression analysis indicated that low level of X1 and X 2 and high level of X3 should be used to manufacture the tablet formulation with desired in % swelling index and % drug release profile . When Polyox 303 was used, % swelling index increased, with increase on the total amount of drug released. Decreasing the amount of HPMC K4M while maintaining the total amount of polymer constant increased the release rate and total amount released. Decreasing the total amount of polymer decreases the swelling and work of penetration, 132 pp. Englisch. Seller Inventory # 9783659355202
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Anti Hypertensive drug- Formulation and its characterization
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LAP LAMBERT Academic Publishing, 2013
ISBN 10: 3659355208
ISBN 13: 9783659355202
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Conventional oral dosage forms provide a specific drug concentration in the systemic circulation without offering any control over the rate of drug delivery. Controlled-release drug delivery systems (CRDDS) provide drug release at a predetermined, predictable, and controlled rate. It was attempt to develop a gastro retentive drug delivery system of anti hypertensive drug using different polymers like that HPMCK4M, Xanthangum, PolyoxWSR303as matrixing agent, swelling agent, respectivel. A simplex lattice design was applied to combined effect of three formulation variables (ie, amount of HPMCK4M (X1), xanthangum (X2), and PolyoxWSR303 (X3). Results of multiple regression analysis indicated that low level of X1 and X 2 and high level of X3 should be used to manufacture the tablet formulation with desired in % swelling index and % drug release profile . When Polyox 303 was used, % swelling index increased, with increase on the total amount of drug released. Decreasing the amount of HPMC K4M while maintaining the total amount of polymer constant increased the release rate and total amount released. Decreasing the total amount of polymer decreases the swelling and work of penetration, Seller Inventory # 9783659355202
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Anti Hypertensive drug- Formulation and its characterization
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ISBN 13: 9783659355202
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Patel RaviProf. Ravi Patel is working as head and Assistant Professor, Dept of Pharmaceutics and Prof. Jitendra Bhangale is working as head and Assistant Professor, Dept of Pharmacology at Shree Saurashtra Patel Sewa Samaj s Smt. N. . Seller Inventory # 5150668
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Anti Hypertensive Drug- Formulation and Its Characterization
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Anti Hypertensive Drug- Formulation and Its Characterization
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Anti Hypertensive Drug- Formulation and Its Characterization
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Anti Hypertensive drug- Formulation and its characterization
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ISBN 13: 9783659355202
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Taschenbuch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Conventional oral dosage forms provide a specific drug concentration in the systemic circulation without offering any control over the rate of drug delivery. Controlled-release drug delivery systems (CRDDS) provide drug release at a predetermined, predictable, and controlled rate. It was attempt to develop a gastro retentive drug delivery system of anti hypertensive drug using different polymers like that HPMCK4M, Xanthangum, PolyoxWSR303as matrixing agent, swelling agent, respectivel. A simplex lattice design was applied to combined effect of three formulation variables (ie, amount of HPMCK4M (X1), xanthangum (X2), and PolyoxWSR303 (X3). Results of multiple regression analysis indicated that low level of X1 and X 2 and high level of X3 should be used to manufacture the tablet formulation with desired in % swelling index and % drug release profile . When Polyox 303 was used, % swelling index increased, with increase on the total amount of drug released. Decreasing the amount of HPMC K4M while maintaining the total amount of polymer constant increased the release rate and total amount released. Decreasing the total amount of polymer decreases the swelling and work of penetrationOmniScriptum SRL, Str. Armeneasca 28/1, office 1, 2012 Chisinau 132 pp. Englisch. Seller Inventory # 9783659355202
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Anti Hypertensive drug- Formulation and its characterization
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ISBN 10: 3659355208
ISBN 13: 9783659355202
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Taschenbuch. Condition: Neu. Anti Hypertensive drug- Formulation and its characterization | Ravi Patel (u. a.) | Taschenbuch | 132 S. | Englisch | 2013 | LAP LAMBERT Academic Publishing | EAN 9783659355202 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu. Seller Inventory # 106028333