Classification of Breast Lesions Using Water Resonance Analysis: A novel non-invasive diagnostic MR tool - Softcover

Diak, Abbie Wood

Softcover

ISBN 10: 3659274402 ISBN 13: 9783659274404

Publisher: LAP LAMBERT Academic Publishing, 2012

Synopsis

In this book you will find a novel non-invasive technique for distinguishing malignant breast lesions from benign breast lesions. The technique involves high spectral and spatial resolution (HiSS) MR imaging, and post-processing of the spectral data utilizing an algorithm to detect non-Lorentzian water resonances. In water, the water resonance is Lorentzian-shaped and symmetric. However, for many reasons, in vivo water resonances often have off-peak non-Lorentzian components. These off-peak components are caused by bulk magnetic susceptibility shifts that result in a superposition of more than one Lorentzian function from a given voxel, centered at a slightly different resonance frequency. Bulk magnetic susceptibility shifts that are likely produce non-Lorentzian lineshapes can be attributed to many factors, such as relatively high levels of paramagnetic deoxygenated blood, interfaces between tissue types, calcifications, etc. The aim of this work was to determine if the presence of large off-peak components are characteristic of malignant lesions. The results demonstrate that this technique could be a useful tool in the diagnosis of breast cancer.

About this title

About the Author

Abbie Wood Diak has always had an interest in Medicine and a passion for Physics. She earned her PhD in Medical Physics from the University of Chicago. She is presently in a residency program in Radiation Physics at MD Anderson Cancer Center. In her spare time she enjoys being with her family, outdoor adventures, and dabbles in fashion design.

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2012
• Language: English
• ISBN 10: 3659274402
• ISBN 13: 9783659274404
• Binding: Paperback
• Number of pages: 128