Resistant Gram Negative Infections: The Challenges Ahead - Softcover

Haque, Shahzad F.; Khan, Asad U.

Softcover

ISBN 10: 3659155586 ISBN 13: 9783659155581

Publisher: LAP LAMBERT Academic Publishing, 2012

Synopsis

The treatment of gram-negative bacteremia is increasingly complicated by the occurrence of multidrug resistant gram-negative bacilli strains. Normally susceptible bacteria may become resistant to antimicrobial agents through mutation and selection or acquisition from other bacteria of genetic information that encodes resistance. Enterobacterial resistance to third-generation cephalosporins is typically caused by production of extended-spectrum beta-lactamases . CTX-Ms are one of the means of antibiotic resistant marker transfer among members of Enterobacteriaceae. Continous surveillance will be necessary to monitor the evolution of extended spectrum beta-lactamases and to verify whether the CTX-M type ESBLs will eventually prevail over the TEM-type ESBLs, which are still widespread, in some areas. The present work unveils the increasing role of the bla-CTX-M ß-lactamases in antibiotic resistance and the significance of appropriate treatment for infections caused by coliforms. Further studies are needed, however, to determine whether antibiotic policies or other measures can halt or lower the level of horizontal transfer that occurs in a hospital or community.

About this title

About the Author

Dr. Shahzad F. Haque,MD(Med),PhD(Med.)Associate Professor,J.N.Medical College&Hospital,Aligarh Muslim University,Aligarh,India,is a well known physician and ardent researcher in the field of Metabolic, Autoimmune and Infectious diseases. He has authored several books, chapters and a number original research papers at national and internationallevel

Edition details

• Publisher: LAP LAMBERT Academic Publishing
• Publication date: 2012
• Language: English
• ISBN 10: 3659155586
• ISBN 13: 9783659155581
• Binding: Paperback
• Number of pages: 204