Skin Cancer: Basic Science, Clinical Research and Treatment: 139 (Recent Results in Cancer Research, 139) - Softcover

Softcover

ISBN 10: 3642787738 ISBN 13: 9783642787737

Publisher: Springer, 2011

Synopsis

In the past two decades, considerable interest in skin cancer has developed in the public and scientific communities. There may have been several reasons for this: - The rise in the global incidence of cutaneous cancers - New molecular biology techniques resulting in a better understanding of pathogenesis and improved diagnostic procedures - The advent of new pathological entities, e. g. , the endemic form of Kaposi's sarcoma - A constantly increasing range of therapeutic modalities, providing even more efficacious treatment and manage­ ment of skin cancers As N. E. Fusenig describes in the first chapter of this volume, basic research is only beginning to unravel the complex mechanism involved in cellular dedifferentiation and tumor progression. Progress is dearly needed, especially in dermato­ oncology, where the rise in the incidence of epithelial tumors has inflated the overall skin cancer incidence. The incidence of tumors of the skin exceeds that of all other neoplasias in humans, with recreational sun exposure being a suspected primary cause. Several studies on the effects of UV radiation have been included at the beginning of this volume. Even the role of long wavelength UV (UVA) has become a focus of research activities. The main concern is that the low carcinogenicity of UVA, in comparison to UVB, may be outweighed and exceeded in its effects by increased UV A exposure, e. g.

Edition details

• Publisher: Springer
• Publication date: 2011
• Language: English
• ISBN 10: 3642787738
• ISBN 13: 9783642787737
• Binding: Paperback
• Number of pages: 456
• Editor: Garbe Claus, Schmitz Stefan, Orfanos Constantin E.