Herpes Simplex Virus: Pathogenesis, Immunobiology and Control: 179 (Current Topics in Microbiology and Immunology, 179) - Softcover

Softcover

ISBN 10: 3642772498 ISBN 13: 9783642772498

Publisher: Springer, 2011

Synopsis

Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control. The virus is large and complex, coding for 70 or more proteins. Although many mysteries remain to be unraveled, our knowledge base regarding genomic organization, gene expression and regulation, pathogenesis, and immune recog­ nition of component parts is quite considerable. Indeed, meet­ ings devoted entirely to herpesviruses are conspicuous by their frequency and excellent, yet sometimes exclusive, attendance. The purpose of this volume is to compile in a single book a series of reviews by leading investigators that deal with various aspects of virus-host interactions and which hopefully will pro­ vide clues as to how to best manage HSV from an immunobio­ logical perspective. Ultimately, one anticipates that a full under­ standing of virus-host interaction will lead to strategies useful for the prevention and control of HSV. The state of current progress with conventional vaccines is presented, as is a chapter on intracellular immunization. This latter novel approach to virus infections comes at approximately the bicentenary of Jenner's introduction of a successful conventional immunization strategy.

Edition details

• Publisher: Springer
• Publication date: 2011
• Language: English
• ISBN 10: 3642772498
• ISBN 13: 9783642772498
• Binding: Paperback
• Number of pages: 189
• Editor: Rouse Barry T.