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Synopsis
Information stored in DNA needs to be translated into functional proteins. Ribonucleoprotein (RNP) particles play a major role in this process. In many autoimmune diseases, antibodies are directed against components of these particles. Detailed protocols for analysing the structure and function of RNPs are described in this manual.
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The maturation of the precursors of mRNA to a functional transcript in eukaryotic cells is a complex, multistep process. It includes the formation of RNP complexes and the splicing procedure. Also, the presence of snRNA packaged as snRNP particles plays an important role in this process. In addition, snRNPs are involved in various autoimmune diseases in which autoantibodies are directed against components of these particles.
Relevant techniques to investigate RNA processing, splicing, protein-RNA complex formation and protein-RNA interactions as well as the use of autoantibodies in basic and clinical research are presented in this manual.
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RNP Particles, Splicing and Autoimmune Diseases (eng)
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RNP Particles, Splicing and Autoimmune Diseases
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Springer Berlin Heidelberg Jul 2012, 2012
ISBN 10: 3642489753
ISBN 13: 9783642489754
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The maturation of the precursors of mRNA to a functional transcript in eukaryotic cells is a complex, multistep process. It includes the formation of RNP complexes and the splicing procedure. Also, the presence of snRNA packaged as snRNP particles plays an important role in this process. In addition, snRNPs are involved in various autoimmune diseases in which autoantibodies are directed against components of these particles. Relevant techniques to investigate RNA processing, splicing, protein-RNA complex formation and protein-RNA interactions as well as the use of autoantibodies in basic and clinical research are presented in this manual. 236 pp. Englisch. Seller Inventory # 9783642489754
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RNP Particles, Splicing and Autoimmune Diseases
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RNP Particles, Splicing and Autoimmune Diseases
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RNP Particles, Splicing and Autoimmune Diseases (Springer Lab Manuals)
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RNP Particles, Splicing and Autoimmune Diseases
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A practical tool for anyone working at the lab benchEasy to follow step-by-step protocolsBackground information and full practical detailsInformation stored in DNA needs to be translated into functional proteins. Ribonucleoprotein (RNP) part. Seller Inventory # 5062487
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Information stored in DNA needs to be translated into functional proteins. Ribonucleoprotein (RNP) particles play a major role in this process. In many autoimmune diseases, antibodies are directed against components of these particles. Detailed protocols for analysing the structure and function of RNPs are described in this manual. Seller Inventory # 9783642489754