Extracellular Matrix in Development (Biology of Extracellular Matrix) - Softcover

Softcover

ISBN 10: 3642427405 ISBN 13: 9783642427404

Publisher: Springer, 2015

Synopsis

Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

About this title

From the Back Cover

Cells in the developing embryo depend on signals from the extracellular environment to help guide their differentiation. An important mediator in this process is the extracellular matrix – secreted macromolecules that interact to form large protein networks outside the cell. During development, the extracellular matrix serves to separate adjacent cell groups, participates in establishing morphogenic gradients, and, through its ability to interact directly will cell-surface receptors, provides developmental clocks and positional information. This volume discusses how the extracellular matrix influences fundamental developmental processes and how model systems can be used to elucidate ECM function. The topics addressed range from how ECM influences early development as well as repair processes in the adult that recapitulate developmental pathways.

The series Biology of Extracellular Matrix is published in collaboration with the American Society for Matrix Biology.

Edition details

• Publisher: Springer
• Publication date: 2015
• Language: English
• ISBN 10: 3642427405
• ISBN 13: 9783642427404
• Binding: Paperback
• Number of pages: 263
• Editor: DeSimone Douglas W., Mecham Robert