Deciphering Growth (Research and Perspectives in Endocrine Interactions) - Softcover

Softcover

ISBN 10: 3642421296 ISBN 13: 9783642421297

Publisher: Springer, 2014

Synopsis

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. Evolution has been characterised by a dramatic increase in an organism’s body size, which is not only limited to the size of the brain.

About this title

From the Back Cover

Growth is a complex process that is essential to life. Not only does size play an important role in the process of cellular proliferation, but body size is also a critical factor in determining which organisms live longer. In mammals, the major factors involved in the regulation of body growth are known: insulin-like growth factors (IGF) are key regulators of somatic growth. Growth hormone (GH), secreted by the pituitary gland, directly regulates circulating levels of IGF-I, which is the major coordinator of spatio-temporal growth of the organism. In humans, growth involves a number of specific characteristics not found in other species. These include rapid intrauterine growth, deceleration just after birth, a mid-childhood growth spurt, a second deceleration before puberty, an adolescent growth spurt, and finally full statural growth, which is seen somewhat later. The combined knowledge concerning the endocrine and paracrine aspects of growth have led to the introduction of treatment regimens, most effective in GH-deficient children.

Edition details

• Publisher: Springer
• Publication date: 2014
• Language: English
• ISBN 10: 3642421296
• ISBN 13: 9783642421297
• Binding: Paperback
• Number of pages: 168
• Editor: Carel J.-C., Kelly Paul A.