Signaling Mechanisms in Protozoa and Invertebrates: v. 17 (Progress in Molecular and Subcellular Biology) - Hardcover

Hardcover

ISBN 10: 354060796X ISBN 13: 9783540607960

Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1996

Synopsis

Comparative endocrinology helps to find the roots of homeostatic regulation in organisms. In this context, many years ago a series of experiments were done, which demonstrated the hormonal regula- tion also on the invertebrate level. The mechanisms are partly similar, partly different, from those found in vertebrates. The new receptor era of mammalian endocrinology stimulated research on invertebrate hormone receptors, and sophisticated methods are applied also to determine hormones. The experiments demonstrated the existence and even similar function of these structures and signaling molecules. However, data on hormones and receptors at the lowest level of metazoan life and the highest level of protozoan life were not at our disposal. About two decades ago, first observations on the presence of hormone receptors reacting to vertebrate hormones in protozoa were made. Since the early 1980s we know that hormone-like molecules similar to those of higher vertebrates are present also in unicellular organisms. The presence of some second messengers in Tetrahymena was recognized. Since then, the research has been extended and many structures - previously believed to be solely vertebrate characteristics, such as opiate receptors, similar to mammalian ones - were found in unicellular organisms. These observations justified the assumption of a complete endocrine system at protozoan level, where - considering the unicellularit- this seemed to be not required. However, it became clear that the roots of endocrine communication date back at least 2 billion years.

About this title

Synopsis

The striking similarities between elements of the mammalian endocrine systems and those of protozoans and invertebrates mean that research which is more easily carried out on simpler organisms has considerable significance for the study of endocrinology in higher organisms. Starting with the presence of hormones and development and function of receptors in protozoa, through the second messenger systems, GPI-expression, signal recognition and pheromone function, this work demonstrates the universality of basic endocrine mechanisms os the living world, as well as the specialities at lower phylogenetic levels.

Edition details

• Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Publication date: 1996
• Language: English
• ISBN 10: 354060796X
• ISBN 13: 9783540607960
• Binding: Hardcover
• Number of pages: 225
• Editor: Csaba Gyorgy, Muller Werner E. G.