This text covers both somatic gene therapy of inherited human diseases as well as of cancer, with emphasis on malignancies of the haematopoietic system. Topics include the isolation and development of haematopietic stem cells, genes involved in development and diseases, methods of gene transfer, carrying out gene transfer, oncogenes and antioncogenes as targets for gene therapy, receptors and their ligands in normal development and diseases, immunology and immunotherapy, radiation biology, clinical leukaemias and bone marrow transplantation
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This text covers both somatic gene therapy of inherited human diseases as well as of cancer, with emphasis on malignancies of the haematopoietic system. Topics include the isolation and development of haematopietic stem cells, genes involved in development and diseases, methods of gene transfer, carrying out gene transfer, oncogenes and antioncogenes as targets for gene therapy, receptors and their ligands in normal development and diseases, immunology and immunotherapy, radiation biology, clinical leukaemias and bone marrow transplantation
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