Intermediate Filament Structure (Molecular Biology Intelligence Unit) - Hardcover

Parry, David A. D.; Steinert, Peter M.

Hardcover

ISBN 10: 3540590803 ISBN 13: 9783540590804

Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1995

Synopsis

This book is about the structure and role of intermediate filament (IF) proteins in a diversity of cell types, including neurones and those from the epithelium. Part of the text is devoted to a discussion of the expression of IF proteins, the hierarchical assembly of those proteins into molecules, oligomers, protofilaments, protofibrils and finally intact IF, and the spatial organization of bundles of these IF within the cytoplasm and the nuclear lamina. IF-associated proteins (IFAPs), which may modulate aggregation or function, are also considered in this context. The final topic that is considered centers on the recent and exciting developments in the area of skin diseases, which have been related directly to IF pathology and to mutation in specific keratin chains.

Edition details

• Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Publication date: 1995
• Language: English
• ISBN 10: 3540590803
• ISBN 13: 9783540590804
• Binding: Hardcover
• Number of pages: 192