Synopsis
The International Life Sciences Institute (ILSI) was established in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooper- ation in these programs among scientists in universities, industry, and government agencies to assist in the resolu- tion of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to har- monize toxicologic testing, to advance a more uniform in- terpretation of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scien- tists. The Monographs on the Pathology of Laboratory Animals are designed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others concerned with evaluating toxicity and carcinogen- icity studies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our ex- pectations that understanding and cooperation will be im- proved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on the eye and ear, is the tenth volume of a set prepared under the sponsorship of the International Life Sciences Institute (ILSI).
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Synopsis
This volume is one of a set of illustrated studies of natural and experimental lesions in laboratory animals (rat, mouse and hamster). Differential diagnostic criteria and terminology are given. Useful data on pathogenesis, aetiology, biologic behaviour and frequency in different stra ins and under varying laboratory conditions are included. The significance of each lesion is considered, and comparisons are made with other species, including man. These monographs are designed to improve communication among those involved in the safety testing of foods, drugs and chemicals. Each volume covers a different organ system.
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