Adalat: A Comprehensive Review - Hardcover

Hardcover

ISBN 10: 3540540334 ISBN 13: 9783540540335

Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. K, 1991

Synopsis

As little as 30 years ago, cardiovascular research at Bayer was just a small sideline with in an environment dominated by chemotherapy research, and only 15 years ago, Bayer's pharmaceutical business was confined to European and Latin Ameri- can countries, with sales in cardiovascular pharmaceuticals close to zero. It goes without saying that Adalat has changed the company as a whole in its research, development, and marketing, both in Germany and, most importantly, world- wide. In research and development, Adalat has led the way in to new areas such as hypertension, acute neurology, dementia, atherosclerosis, and heart failure. In pharmacology, Adalat was present at the dawning of the second phar- macological revolution, which started out from whole animal models and progres- sed, via in vitro screening and pharmacological research on the DHP receptor, down to the molecular level with the cloning of calcium-channel proteins. Having followed the Adalat story closely in its early years as a bench scientist, let me take this opportunity to thank the inventors, the scientists, and the investigators who have helped to tap the broad potential of calcium-channel blockade with dihyd- ropyridines in general and Adalat in particular. But, success should not obscure our vision. There is no reason for us to rest on our laurels: it will take true innovations in cardiovascular research to top the gold standard set by Adalat. Let us take up the challenge.

About this title

Synopsis

This volume documents the Adalat story, from its beginnings in research and development to its pioneering role in new areas of pharmacological treatment. Adalat is shown to have already set a standard in the pharmacology of afflictions such as hypertension, acute neurology, dementia, atherosclerosis and heart failure. In exploring the Adalat treatment, the book surveys a unique chapter in the history of cardiovascular research.

Edition details

• Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
• Publication date: 1991
• Language: English
• ISBN 10: 3540540334
• ISBN 13: 9783540540335
• Binding: Hardcover
• Number of pages: 252
• Editor: Lichtlen P.R., Reale A.