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Synopsis
This volume is based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I Conference in 2006. Written by experts in the field, it addresses a critical topics relating to late effects, such as mechanisms of injury, the role of screening, options for interventions, second malignancies, and prevention. It is hoped that these findings will help readers to prevent and treat the long-term side-effects of irradiation.
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From the Back Cover
The search for the most favorable therapeutic ratio – at which ablation of cancer is achieved while normal tissues are conserved – has been modern radiation oncology’s equivalent of the quest for the Holy Grail. Our awareness of the late effects of radiation grew during the past century as new modalities were introduced. Heightened normal tissue reactions accompanied the higher rates of cancer ablation achieved by escalation of radiation doses, accelerated fractionated radiotherapy, and aggressive concurrent chemotherapy and radiation regimens. This volume is based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006. Written by experts in the field, it addresses a number of critical topics relating to late effects, such as mechanisms of injury, the role of screening, options for interventions, second malignancies, and prevention. It is hoped that it will assist the reader in understanding how to prevent and treat the long-term side-effects of irradiation.
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CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues (Medical Radiology)
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CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues (Medical Radiology)
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Condition: New. pp. xxii + 144 Illus. Seller Inventory # 7545779
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CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues (Medical Radiology)
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Cured I Lent Late Effects Of Cancer Treatment On Normal Tissues (Hb 2007)
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Cured I - Lent Late Effects Of Cancer Treatment On Normal Tissues (Hb)
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CURED I LENT LATE EFFECTS OF CANCER TREATMENT ON NORMAL TISSUES (HB 2007)
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Late effects of cancer treatment on normal tissues.
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soft cover. Condition: Wie neu. Gebraucht - Wie neu -The rapid advances in radiation oncology, radiation biology, and radiation therapy physics have led to an accumulation of information on the interactions of radiation with other therapeutic modalities, such as the wide array of chemotherapeutic agents being employed in combination with radiation therapy, as well as the multiple biologic response modi ers that are being used in combination with radiation therapy. It is now recognized that they have a signi cant impact on normal tissue toxicities. The radiation doses customarily deemed safe on the basis of past experience have now, when combined with other modalities, led to severe late effects in different vital organs. The previously de ned radiation tolerance dosages remain as valuable guides, but their applicability has changed signi cantly. The emphasis is now placed on the volume of the organ irradiated, as well as the dose being used. New constructs rel- ing global (whole organ) and focal (partial volume) injury as a function of the dose volume histogram emerge as a signi cant predictor of late effects on normal tissues. There are now mathematical models such as the model on standard dose, time-dose factors, and accumulated radiation effects that have been supplanted by linear-q- dratic equations using the alpha/beta ratio and its clinical applicability to normal tissue complications. This volume presents contemporary data relating to late effects on normal tissues. Seller Inventory # 22441
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Late Effects of Cancer Treatment on Normal Tissues
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Condition: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar. Seller Inventory # 3568307/12
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CURED I - LENT Late Effects of Cancer Treatment on Normal Tissues
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Springer, Berlin, Springer Berlin Heidelberg, Springer, 2007
ISBN 10: 3540490698
ISBN 13: 9783540490692
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Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The rapid advances in radiation oncology, radiation biology, and radiation therapy physics have led to an accumulation of information on the interactions of radiation with other therapeutic modalities, such as the wide array of chemotherapeutic agents being employed in combination with radiation therapy, as well as the multiple biologic response modi ers that are being used in combination with radiation therapy. It is now recognized that they have a signi cant impact on normal tissue toxicities. The radiation doses customarily deemed safe on the basis of past experience have now, when combined with other modalities, led to severe late effects in different vital organs. The previously de ned radiation tolerance dosages remain as valuable guides, but their applicability has changed signi cantly. The emphasis is now placed on the volume of the organ irradiated, as well as the dose being used. New constructs rel- ing global (whole organ) and focal (partial volume) injury as a function of the dose volume histogram emerge as a signi cant predictor of late effects on normal tissues. There are now mathematical models such as the model on standard dose, time-dose factors, and accumulated radiation effects that have been supplanted by linear-q- dratic equations using the alpha/beta ratio and its clinical applicability to normal tissue complications. This volume presents contemporary data relating to late effects on normal tissues. 140 pp. Englisch. Seller Inventory # 9783540490692