Medical Image Computing and Computer-Assisted Intervention - MICCAI 2000: Third International Conference Pittsburgh, PA, USA, October 11-14, 2000 ... (Lecture Notes in Computer Science, 1935) - Softcover

Softcover

ISBN 10: 3540411895 ISBN 13: 9783540411895

Publisher: Springer, 2000

Synopsis

In previous work [6], we presented a novel information theoretic approach for calculating fMRI activation maps. The information-theoretic approach is - pealing in that it is a principled methodology requiring few assumptions about the structure of the fMRI signal. In that approach, activation was quanti?ed by measuring the mutual information (MI) between the protocol signal and the fMRI time-series at a givenvoxel.This measureis capable of detecting unknown nonlinear and higher-order statistical dependencies. Furthermore, it is relatively straightforward to implement. In practice,activation decisions at eachvoxelareindependent of neighboring voxels. Spurious responses are then removed by ad hoc techniques (e.g. morp- logicaloperators).Inthispaper,wedescribeanautomaticmaximumaposteriori (MAP) detection method where the well-known Ising model is used as a spatial prior.The Isingspatialpriordoes not assumethat the time-seriesofneighboring voxelsareindependentofeachother.Furthermore,removalofspuriousresponses is an implicit component of the detection formulation. In order to formulate the calculation of the activation map using this technique we ?rst demonstrate that the information-theoretic approach has a natural interpretation in the hypo- esis testing framework and that, speci? cally, our estimate of MI approximates the log-likelihood ratio of that hypothesis test. Consequently, the MAP det- tion problem using the Ising model can be formulated and solved exactly in polynomial time using the Ford and Fulkerson method [4]. We compare the results of our approach with and without spatial priors to an approachbased on the general linear model (GLM) popularized by Fristonet al [3]. We present results from three fMRI data sets. The data sets test motor, auditory, and visual cortex activation, respectively.

About this title

Synopsis

This book constitutes the refereed proceedings of the Third International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2000, held in Pittsburgh, PA, USA in October 2000. The 136 papers presented were carefully reviewed and selected from a total of 194 submissions. The book offers topical sections on neuroimaging and neuroscience, segmentation, oncology, medical image analysis and visualization, registration, surgical planning and simulation, endoscopy and laparoscopy, cardiac image analysis, vascular image analysis, visualization, surgical navigation, medical robotics, plastic and craniofacial surgery, and orthopaedics.

Edition details

• Publisher: Springer
• Publication date: 2000
• Language: English
• ISBN 10: 3540411895
• ISBN 13: 9783540411895
• Binding: Paperback
• Number of pages: 1304
• Editor: Delp Scott L., DiGoia Anthony M., Jaramaz Branislav