Modelling in Molecular Biology (Natural Computing Series) - Hardcover

Hardcover

ISBN 10: 3540407995 ISBN 13: 9783540407997

Publisher: Springer, 2004

Synopsis

This volume is based on the workshop“Modelling in Molecular Biology” that tookplacein2002inSingapore. Themaingoaloftheworkshopwastopresent models/methods used in solving some fundamental problems in biosciences. The volume consists of a selection of papers presented at the workshop as well as of some other papers that are included so that the presentation of the theme of the workshop is broader and more balanced. As a matter of fact we feel that the collection of papers comprising this volume represents a wide spectrum of quite diverse ideas and trends. The paper by D. A. Beard et al. explores the common thesis that und- standingthebehaviouroflargeinteractingsystemsofmanyenzymesandre- tants underlies the modelling and simulation of whole-cell systems. Moreover, the models need to represent the basic stoichiometry, with balanced che- cal reactions and the conservation of mass, energy and charge. The authors discuss the stoichiometric and then kinetic details of approaches to modelling and simulation of biochemical systems. P. R. A. Campos et al. are concerned with models of evolution and adaptation (which is essential for precise - derstanding of molecular phylogeny). In particular, their paper is concerned with the rate of adaptation of asexual organisms(which is important because it in?uences the speed of the assumed molecular clock). It is known that for such organisms the rate of adaptation does not steadily increase with the - creasing rate of advantageous mutations, and this paper studies the mutual interference of two advantageous mutants that are each initially present in only a single organism.

About this title

About the Author

G. Ciobanu is Professor at the Romanian Academy, Institute of Computer Science and has received the first "Grigore Moisil" award for theoretical computer science offered by the Romanian Academy. Over 60 papers published in international journals.

G. Rozenberg is multiple Springer author and editor of books and series (EATCS, NCS).

From the Back Cover

This volume consists of papers concerned with models and methods used in solving some fundamental problems of biosciences. They represent a wide spectrum of diverse ideas and trends. In particular, they reflect the genuinely interdisciplinary nature of research on modelling in molecular biology – the inspiration, ideas and techniques presented in this volume come from mathematics, computer science, statistics, chemistry and biology.

Edition details

• Publisher: Springer
• Publication date: 2004
• Language: English
• ISBN 10: 3540407995
• ISBN 13: 9783540407997
• Binding: Hardcover
• Number of pages: 315
• Editor: Ciobanu Gabriel, Rozenberg Grzegorz