Molecular Modeling: Basic Principles and Applications: Vol 3 (Methods and Principles in Medicinal Chemistry) - Hardcover

Hardcover

ISBN 10: 3527293841 ISBN 13: 9783527293841

Publisher: Wiley VCH, 1996

Synopsis

This is an introduction to the foundations and applications of molecular modelling for researchers in industry and universities. Starting from basic principles, it shows how to avoid common pitfalls and enables the reader to model proteins and other relevant biomolecules.

About this title

Review

"If the currently popular 'Dummies' series of computer books were to publish a volume on molecular modeling this would be it" (J. Am. Chem. Soc.) "The book is well written and assumes no prior knowledge of molecular biology, statistical mechanics, or quantum chemistry ... . The authors ... provide practical hints for the application of the majority of available programs in computational chemistry" (Computers in Physics) "Of particular benefit to the novice modeller is the inclusion of a discussion of the limitations of several molecular modelling programs" (Scientific Computing World)

From the Back Cover

Creating a computer model of a molecule with known or unknown structure that can then be studied by computational means is a key skill for biochemists, molecular biologists and aspiring drug developers. Increasingly sophisticated modeling software requires at least a basic understanding of the method in order to avoid misinterpretation of the data generated.
Ideal for beginners, this book explains the basics of modeling in a competent yet easily understandable way, with completely worked–out examples to guide readers to their first modeling experiments.
This third edition features a new chapter on chemogenomics, reflecting the trend towards ′chemical biology′, while the example of protein modeling is completely rewritten for a better ′feel′ of modeling complex biomolecules.
The authors are experienced university lecturers who regularly hold courses on molecular modeling, making this a tried–and–tested text for teachers. It is equally valuable for experts, since it is the only book to evaluate the strengths and limitations of the molecular modeling techniques and software currently available.

Edition details

• Publisher: Wiley VCH
• Publication date: 1996
• Language: English
• ISBN 10: 3527293841
• ISBN 13: 9783527293841
• Binding: Hardcover
• Number of pages: 206
• Editor: Höltje Hans–Dieter, Folkers Gerd