Biological Exposure Values for Occupational Toxicants and Carcinogens: Critical Data Evaluation for BAT and EKA Values, Volume 2: v. 2 (The ... Part II: BAT ValueDocumentations (DFG)) - Softcover

Softcover

ISBN 10: 3527270345 ISBN 13: 9783527270347

Publisher: Wiley VCH, 1995

Synopsis

Threshold limit values indicate the point at which health is impaired by chemicals. They are indispensable in occupational medicine for evaluating the risk of working materials. Biological Tolerance Values (BAT Values) give the threshold limits for hazardous occupational toxicants in body fluids. They are predominantly used in Europe. This volume provides the scientific reasons why 12 important BAT Values were established at a particular level. The documentations include pharmacokinetics, critical toxicity, exposure and effect, selection of the indicators, methodology, background exposure, interpretation of the data. Further 10 evaluations for carcinogenic substances are given (e.g. arsenic trioxide, ethylene oxide, hydrazine, nickel and vinyl chlorides). For the first time, monitoring by measuring haemoglobin adducts is described.

About this title

From the Back Cover

All volumes of the MAK–Collection provide comprehensive and authoritative information for occupational health and safety professionals and researchers. They cover both the toxicological substantiation of threshold values for chemicals at the workplace (MAK and BAT values) and the suitable monitoring methods. Thus, they are an indispensable tool for maintaining occupational health and safety. Here, the documentations for the established BAT values (Biological Tolerance Values) and EKA (Exposure Equivalents for Carcinogenic Substances) as well as for further biological exposure values are provided. These include an authoritative review of the available toxicological studies and data. For every substance, metabolism and pharmacokinetics, critical toxicity, exposure and effects, suitable indicators of internal exposure, the evaluation of the BAT value and the correct interpretation of data are described. Basic physico–chemical data are provided as well. The documentations are thus not only essential for the application of BAT and EKA values but provide a concise overview of biological monitoring for each substance. The documentations are authoritative, because they were compiled by the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. The Commission is internationally acknowledged for its neutrality and is working strictly according to transparent, scientific criteria. BAT Values set the standards for legal regulations in many countries of the world.

About the Author

Hans Drexler is head of the working group "Setting of Threshold Limit Values in Biological Materials" of the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area and Director of the Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine of the University of Erlangen–Nuremberg (Germany). He is board member of the International Society of Environmental Medicine (ISEM) and Editor–in–chief of the International Archives of Occupational and Environmental Health.

Edition details

• Publisher: Wiley VCH
• Publication date: 1995
• Language: English
• ISBN 10: 3527270345
• ISBN 13: 9783527270347
• Binding: Paperback
• Number of pages: 236
• Editor: Greim Helmut, Lehnert Gerhard