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Bioanalytical Investigation:Management of Hypertension Using Doxazosin: Doxazosin using internal standard doxazosin D8 by LC/MS/MS system used in the management of hypertension - Softcover

 
9783330074835: Bioanalytical Investigation:Management of Hypertension Using Doxazosin: Doxazosin using internal standard doxazosin D8 by LC/MS/MS system used in the management of hypertension

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Development in the bioanalytical technology & the application of pharmacokinetic (PK) principles has created a synergistic partnership that plays a vital, influential role in the discovery and development of new medicines. In the bioanalytical investigation a fast, sensitive, accurate and reproducible high performance liquid chromatography-mass spectrometry method has been developed & validated for the quantitative estimation of DOXAZOSIN in human plasma using DOXAZOSIN D8 used as internal standard by solid phase extraction (SPE) technique.Doxazosin, is an oral drug used for treating high blood pressure and symptoms of benign prostatic hyperplasia, it belongs to the class of alpha -1 adrenergic blockers. It prevents Norepinephrine that is released by nerves from binding to alpha -1 receptors on smooth muscles surrounding blood vessels and in prostate and bladder by blocking the effect of norepinephrine, Doxazosin relaxes the smooth muscles, relaxation of smooth muscle surrounding blood vessels causes them to enlarge (dilate) and thereby reduces blood pressure.

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  • PublisherLAP LAMBERT Academic Publishing
  • Publication date2017
  • ISBN 10 3330074833
  • ISBN 13 9783330074835
  • BindingPaperback
  • LanguageEnglish
  • Number of pages168

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Anil Kumar Sahdev
ISBN 10: 3330074833 ISBN 13: 9783330074835
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Development in the bioanalytical technology & the application of pharmacokinetic (PK) principles has created a synergistic partnership that plays a vital, influential role in the discovery and development of new medicines. In the bioanalytical investigation a fast, sensitive, accurate and reproducible high performance liquid chromatography-mass spectrometry method has been developed & validated for the quantitative estimation of DOXAZOSIN in human plasma using DOXAZOSIN D8 used as internal standard by solid phase extraction (SPE) technique.Doxazosin, is an oral drug used for treating high blood pressure and symptoms of benign prostatic hyperplasia, it belongs to the class of alpha -1 adrenergic blockers. It prevents Norepinephrine that is released by nerves from binding to alpha -1 receptors on smooth muscles surrounding blood vessels and in prostate and bladder by blocking the effect of norepinephrine, Doxazosin relaxes the smooth muscles, relaxation of smooth muscle surrounding blood vessels causes them to enlarge (dilate) and thereby reduces blood pressure. 168 pp. Englisch. Seller Inventory # 9783330074835

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Anil Kumar Sahdev|Monika Bhandari|Khushboo Gupta
Published by LAP LAMBERT Academic Publishing, 2017
ISBN 10: 3330074833 ISBN 13: 9783330074835
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Sahdev Anil KumarAnil Kumar Sahdev* (Assistant Professor), Monika Bhandari ( M.Pharma), Khushboo Gupta (M.Pharma)Innovative College of Pharmacy, Greater Noida (Uttar Pradesh).IndiaDevelopment in the bioanalytical technology & the. Seller Inventory # 151236521

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Published by LAP LAMBERT Academic Publishing, 2017
ISBN 10: 3330074833 ISBN 13: 9783330074835
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Development in the bioanalytical technology & the application of pharmacokinetic (PK) principles has created a synergistic partnership that plays a vital, influential role in the discovery and development of new medicines. In the bioanalytical investigation a fast, sensitive, accurate and reproducible high performance liquid chromatography-mass spectrometry method has been developed & validated for the quantitative estimation of DOXAZOSIN in human plasma using DOXAZOSIN D8 used as internal standard by solid phase extraction (SPE) technique.Doxazosin, is an oral drug used for treating high blood pressure and symptoms of benign prostatic hyperplasia, it belongs to the class of alpha -1 adrenergic blockers. It prevents Norepinephrine that is released by nerves from binding to alpha -1 receptors on smooth muscles surrounding blood vessels and in prostate and bladder by blocking the effect of norepinephrine, Doxazosin relaxes the smooth muscles, relaxation of smooth muscle surrounding blood vessels causes them to enlarge (dilate) and thereby reduces blood pressure. Seller Inventory # 9783330074835

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Anil Kumar Sahdev
Published by LAP LAMBERT Academic Publishing, 2017
ISBN 10: 3330074833 ISBN 13: 9783330074835
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Paperback. Condition: Brand New. 168 pages. 8.66x5.91x0.38 inches. In Stock. Seller Inventory # 3330074833

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