Extracellular Matrix in Tumor Biology (Biology of Extracellular Matrix) - Hardcover

Book 19 of 25: Biology of Extracellular Matrix
 
9783319609065: Extracellular Matrix in Tumor Biology (Biology of Extracellular Matrix)
Hardcover
ISBN 10: 3319609068 ISBN 13: 9783319609065
Publisher: Springer, 2017

Synopsis

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression.  The book addresses researchers working on cancer biology or ECM, and oncologists alike.

"synopsis" may belong to another edition of this title.

About the Author

​Rolf Brekken is Professor of Surgery and Pharmacology and Deputy Director of the Hamon Center Therapeutic Oncology Research at UT Southwestern. Dr. Brekken’s laboratory studies ECM signaling in tumors, therapeutic immune reactivation and how immune cells contribute to the metastatic cascade. He has authored over 150 peer-reviewed publications and is currently a senior editor at Cancer Research. 

Dwayne Stupack is an associate professor of Reproductive Medicine and Pathology at the University of California San Diego, Moore’s Cancer Center.  Dr. Stupack’s laboratory work has been focused on the intersection of extracellular matrix signaling, the presentation of different forms of the same matrix to cells, and cell survival during tumor metastasis.  A past councilor of the American Society for Matrix Biology with more than 90 publications, Dr. Stupack currently edits the Society’s Matrix Letter.

From the Back Cover

This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression.  The book addresses researchers working on cancer biology or ECM, and oncologists alike.

"About this title" may belong to another edition of this title.

Publisher
Springer
Publication date
2017
Language
English
ISBN 10 
3319609068
ISBN 13 
9783319609065
Binding
Hardcover
Edition number
1
Number of pages
124
Editor
Brekken Rolf A., Stupack Dwayne

Other Popular Editions of the Same Title

9783319869568: Extracellular Matrix in Tumor Biology (Biology of Extracellular Matrix)

Featured Edition

ISBN 10:  3319869566 ISBN 13:  9783319869568
Publisher: Springer, 2018
Softcover