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Rapid Cell Magnetisation Using Cationised Magnetoferritin (Springer Theses) - Hardcover

Book 293 of 797: Springer Theses

Correia Carreira, Sara

 
9783319603322: Rapid Cell Magnetisation Using Cationised Magnetoferritin (Springer Theses)

Synopsis

Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.

 

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From the Back Cover

Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.

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Other Popular Editions of the Same Title

9783319868387: Rapid Cell Magnetisation Using Cationised Magnetoferritin (Springer Theses)

Featured Edition

ISBN 10:  3319868381 ISBN 13:  9783319868387
Publisher: Springer, 2018
Softcover