Genome Editing in Neurosciences (Research and Perspectives in Neurosciences) - Hardcover

Hardcover

ISBN 10: 3319601911 ISBN 13: 9783319601915

Publisher: Springer, 2017

Synopsis

This book is open access under a CC BY 4.0 license.

CRISPR-Cas9 is a rapid, efficient, versatile and relatively cheap method for dissecting the molecular pathways that are the basis of life, as well as for investigating and potentially rectifying faults in these pathways that result in disease.

This book reviews how CRISPR-Cas9 and other genome editing techniques are advancing our understanding of development and function in the nervous system, uncovering the molecular causes of neurological disorders and providing tools for gene therapy.

About this title

About the Author

Rudolf Jaenisch, MIT Cambridge, USA

Feng Zhang, MIT Cambridge, USA

Fred Gage, Salk Institute for Biological Studies, La Jolla, CA, USA

From the Back Cover

This book is open access under a CC BY 4.0 license.

Innovations in molecular biology are allowing neuroscientists to study the brain with unprecedented resolution, from the level of single molecules to integrated gene circuits. Chief among these innovations is the CRISPR-Cas genome editing technology, which has the precision and scalability to tackle the complexity of the brain. This Colloque Médecine et Recherche has brought together experts from around the world that are applying genome editing to address important challenges in neuroscience, including basic biology in model organisms that has the power to reveal systems-level insight into how the nervous system develops and functions as well as research focused on understanding and treating human neurological disorders.

Edition details

• Publisher: Springer
• Publication date: 2017
• Language: English
• ISBN 10: 3319601911
• ISBN 13: 9783319601915
• Binding: Hardcover
• Edition number: 1
• Number of pages: 134
• Editor: Jaenisch Rudolf, Zhang Feng, Gage Fred