Microdomains in the Cardiovascular System: 3 (Cardiac and Vascular Biology, 3) - Hardcover

Hardcover

ISBN 10: 3319545787 ISBN 13: 9783319545783

Publisher: Springer, 2017

Synopsis

The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.

This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology. 

About this title

About the Author

Prof. Viacheslav Nikolaev, PhD is the Director of the Institute of Experimental Cardiovascular Research at the University Medical Center Hamburg-Eppendorf, Germany. He is also a member of the German Center for Cardiovascular Research (DZHK). His main interest is live-cell imaging of cardiac cAMP and cGMP microdomains and their role in heart failure.

 

Prof. Manuela Zaccolo, MD is the Director of the Burdon Sanderson Cardiac Science Centre and works in the Department of Physiology, Anatomy and Genetics at the University of Oxford. She is interested in the regulatory principles by which intracellular signalling networks achieve the plasticity and context-sensitivity necessary for a cell to function. A central topic of her research is the role of local regulation of cyclic nucleotide signalling in healthy and diseased hearts.   

From the Back Cover

The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future.

This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.

Edition details

• Publisher: Springer
• Publication date: 2017
• Language: English
• ISBN 10: 3319545787
• ISBN 13: 9783319545783
• Binding: Hardcover
• Edition number: 1
• Number of pages: 394
• Editor: Nikolaev Viacheslav, Zaccolo Manuela