Synopsis
This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
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About the Author
David P. Bazett-Jones
The Hospital for Sick Children, Toronto, ON, Canada
Graham Dellaire
Dalhousie University, Halifax, NS, Canada
From the Back Cover
This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.
"About this title" may belong to another edition of this title.
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The Functional Nucleus (eng)
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The Functional Nucleus
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Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides a state-of-the-art review on nuclear structure and functions Highlights the relation between epigenomics and nuclear architectureGives an outlook on possible medical applicationsProvides a. Seller Inventory # 120076241
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The Functional Nucleus
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ISBN 10: 3319388800
ISBN 13: 9783319388809
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Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book gives an in-depth overview on nuclear structure and function. It clearly shows that theepigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice. 520 pp. Englisch. Seller Inventory # 9783319388809
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The Functional Nucleus
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Buch. Condition: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book gives an in-depth overview on nuclear structure and function. It clearly shows that the epigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 520 pp. Englisch. Seller Inventory # 9783319388809
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The Functional Nucleus
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Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book gives an in-depth overview on nuclear structure and function. It clearly shows that theepigenome and the three-dimensional organization of the nucleus are not independent properties. The intimate relationship between the location and the epigenetic modifications of gene loci is highlighted. Finally, it shows that the complex three-dimensional organization of the nucleus is not just of academic interest: The structure, composition and function of virtually all of the sub-nuclear compartments identified so far can be implicated to a list of human genetic diseases. Hence, a detailed elucidation of how these domains are assembled and function will provide new opportunities for therapeutic intervention in clinical practice. Seller Inventory # 9783319388809
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The Functional Nucleus
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