Frontiers in Biotransformation: Volume 7: Relationships between Structur and Function of Cytochrome P–450 Experiments, Calculations, Models Frontiers in Biotransformation: Vol 7 - Hardcover

Ruckpaul, K

Hardcover

ISBN 10: 3055013298 ISBN 13: 9783055013294

Publisher: Wiley VCH, 1992

Synopsis

A challenging task for bioscientists has always been and still is the question of how a distinct enzymatic function is encoded in a corresponding molecular structure. Genetic engineering techniques, computer aided calculations and sophisticated experimental techniques nowadays provide facilities to make a deeper understanding of structure-function relationships a realistic aim. Volume Seven of this series comprehends data which represent seminal developments in this field. The contributions cover a broad scope ranging from 3rd-structure studies of engineered protein molecules to understand the functional importance of distinct amino acids, calculations of the active site specificities with respect to reaction mechanisms and prediciton of membrane topology supported by experimental data. Internationally acknowledged experts present in 10 articles an updated view of structure-function relationships of the key enzyme in biotransformation.

About this title

About the Author

Editors' affiliations: Klaus Ruckpaul, born in 1930, and Horst Rein, born in 1932, are professors at the Max Delbrueck Centre for Molecular Medicine in Berlin-Buch. Their field of activity covers studies on enzymes involved in the biotransformation of hormones, medicinal products and in the activation of environmental toxins.

Edition details

• Publisher: Wiley VCH
• Publication date: 1992
• Language: English
• ISBN 10: 3055013298
• ISBN 13: 9783055013294
• Binding: Hardcover
• Number of pages: 378