Extracellular Matrix in Development and Disease - Softcover

Softcover

ISBN 10: 3038975702 ISBN 13: 9783038975700

Publisher: Mdpi AG, 2019

Synopsis

The extracellular matrix in development and disease deals with the molecular and cellular aspects of development and disease. Cells exist in three-dimensional scaffolding called the extracellular matrix. The matrix holds together the millions of cells that make up our blood vessels, organs, skin, and all tissues of the body. The matrix serves as a reservoir of signaling molecules as well. In bacterial cultures, biofilms form as an extracellular matrix and play essential roles in disease and drug resistance. Topics such as matrix structure and function, cell attachment and cell surface proteins mediating cell-matrix interactions, synthesis, regulation, composition, structure, assembly, remodeling, and function of the matrix are included. A common thread uniting the topics is the essential nature that the matrix plays in normal development and pathophysiology. Providing new knowledge will lead us to improved diagnostics, the preventions of disease progression, and therapeutic strategies for the repair and regeneration of tissues. Topics such as the extracellular matrix in hereditary diseases, reproduction, cancer, muscle, and tissue engineering applications, and diverse roles for integrins, are included in this collection.

Edition details

• Publisher: Mdpi AG
• Publication date: 2019
• Language: English
• ISBN 10: 3038975702
• ISBN 13: 9783038975700
• Binding: Paperback
• Number of pages: 356
• Editor: Oxford Julia Thom