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Matrix Metalloproteinase Inhibitors: Specificity of Binding and Structure-Activity Relationships: 103 (Experientia Supplementum, 103) - Softcover
Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results in tissue degradation, producing a wide array of disease processes such as rheumatoid arthritis, osteoarthritis, tumor growth and metastasis, multiple sclerosis, congestive heart failure, and others. Thus MMP inhibitors are candidates for therapeutic agents to combat a number of diseases. The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases. The articles focus specifically on structure-activity relationships of all classes of compounds and on their modes of action and specificity of binding with the receptors based on experimental and theoretical studies. These studies constitute a valuable asset for all those involved in drug development.
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- PublisherSpringer
- Publication date2014
- ISBN 10 3034807643
- ISBN 13 9783034807647
- BindingPaperback
- Number of pages296
- EditorGupta Satya Prakash
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Matrix Metalloproteinase Inhibitors : Specificity of Binding and Structure-Activity Relationships
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Matrix Metalloproteinase Inhibitors: Specificity of Binding and Structure-Activity Relationships (Experientia Supplementum, 103)
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Matrix Metalloproteinase Inhibitors
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Book Description Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results in tissue degradation, producing a wide array of disease processes such as rheumatoid arthritis, osteoarthritis, tumor growth and metastasis, multiple sclerosis, congestive heart failure, and others. Thus MMP inhibitors are candidates for therapeutic agents to combat a number of diseases. The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases. The articles focus specifically on structure-activity relationships of all classes of compounds and on their modes of action and specificity of binding with the receptors based on experimental and theoretical studies. These studies constitute a valuable asset for all those involved in drug development. 296 pp. Englisch. Seller Inventory # 9783034807647
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Book Description Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Focus on quantitative structure-activity relationship of MMP inhibitors Contains an overview of endogenous tissue inhibitors of MMPs and their biological relevance Written by experts in the fieldMatrix metalloproteinases (MMPs) a. Seller Inventory # 4318357
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Matrix Metalloproteinase Inhibitors : Specificity of Binding and Structure-Activity Relationships
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Book Description Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results in tissue degradation, producing a wide array of disease processes such as rheumatoid arthritis, osteoarthritis, tumor growth and metastasis, multiple sclerosis, congestive heart failure, and others. Thus MMP inhibitors are candidates for therapeutic agents to combat a number of diseases. The present book discusses the design and development of different classes of inhibitors of important classes of MMPs, such as gelatinases and collagenases. The articles focus specifically on structure-activity relationships of all classes of compounds and on their modes of action and specificity of binding with the receptors based on experimental and theoretical studies. These studies constitute a valuable asset for all those involved in drug development. Seller Inventory # 9783034807647
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Matrix Metalloproteinase Inhibitors: Specificity of Binding and Structure-activity Relationships
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Book Description Paperback. Condition: Brand New. 2012 edition. 286 pages. 9.00x6.00x0.80 inches. In Stock. Seller Inventory # x-3034807643
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