The Pharmaceutical Applications of Dimethyl Sulfoxide: From Skin Penetration to Cell Therapy (AAPS Advances in the Pharmaceutical Sciences Series, 30) - Hardcover

Hardcover

ISBN 10: 3032192552 ISBN 13: 9783032192554

Publisher: Springer, 2026

Synopsis

This book provides an in-depth educational review of Dimethyl Sulfoxide (DMSO) and its utility in pharmaceutical drug development with specific focus on topical, parenteral, and biologics applications and formulations. Dimethyl sulfoxide is a widely used but often under-appreciated pharmaceutical material, which is perceived to be primarily confined to discovery research. This book helps to change this perception. This book brings current awareness of this multifunctional material as an API and excipient. This book also summarizes the safety and toxicology of dimethyl sulfoxide as it compares to other aprotic solvents. The intended audience is pharmaceutical scientists, pharmaceutical formulators, researchers, drug development professionals and academics.

About this title

About the Author

Nigel Langley is the Global Technical Director of  Gaylord Chemical Company LLC, which provides technical support to the pharmaceutical industry and helps solve drug formulation challenges. Prior to joining Gaylord Chemical, Nigel has held various senior technical and marketing positions with BASF and Croda International PLC. Nigel has also worked in Japan and England with Croda. He gained his Chemistry (Hons) degree and PhD (liquid crystals) from the University of Hull (UK) and an MBA from Leeds University (UK). He also took a 2- year Postdoctoral research position at Leeds University (UK) in natural product synthesis. He has over 100 scientific publications and has co- edited 2 books. Nigel is an adjunct professor at the University of Mississippi and a Fellow of the Royal Society of Chemistry (UK). In 2018 he was awarded the Industry Research Achievement Award in Excipient Technology by the IPEC Foundation. He has been a member of the Executive Committee at IPEC- Americas since 2010 and is currently Chair. Nigel is on the Medicine Maker’s Power List for 2020, 2021 & 2022.

From the Back Cover

This book provides an in-depth educational review of Dimethyl Sulfoxide (DMSO) and its utility in pharmaceutical drug development with specific focus on topical, parenteral, and biologics applications and formulations. Dimethyl sulfoxide is a widely used but often under-appreciated pharmaceutical material, which is perceived to be primarily confined to discovery research. This book helps to change this perception. This book brings current awareness of this multifunctional material as an API and excipient. This book also summarizes the safety and toxicology of dimethyl sulfoxide as it compares to other aprotic solvents. The intended audience is pharmaceutical scientists, pharmaceutical formulators, researchers, drug development professionals and academics.

Edition details

• Publisher: Springer
• Publication date: 2026
• Language: English
• ISBN 10: 3032192552
• ISBN 13: 9783032192554
• Binding: Hardcover
• Number of pages: 211
• Editor: Langley Nigel, Almarsson Örn, Osborne David W.