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Fc Mediated Activity of Antibodies: Structural and Functional Diversity: 423 (Current Topics in Microbiology and Immunology, 423) - Softcover
Synopsis
This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
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About the Author
Jeffrey V. Ravetch
Theresa and Eugene M. Lang Professor
Department Leonard Wagner Laboratory of Molecular Genetics and Immunology
Rockefeller University
1230 York Avenue, Box 98
New York, NY 10021, USA
ravetch@mail.rockefeller.edu
Falk Nimmerjahn
Professor for Immunology and Genetics
Chairman of the Institute of Genetics
Head of the Department of Biology
Department of Biology
University of Erlangen-Nuernberg
Erwin-Rommelstr. 3
91058 Erlangen, Germanyfalk.nimmerjahn@fau.de
From the Back Cover
This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
"About this title" may belong to another edition of this title.
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Fc Mediated Activity of Antibodies. Structural and Functional Diversity.
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Cham, Switzerland, Springer., 2019
ISBN 10: 3030310558
ISBN 13: 9783030310554
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Fc Mediated Activity of Antibodies: Structural and Functional Diversity (Current Topics in Microbiology and Immunology)
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Fc Mediated Activity of Antibodies
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ISBN 10: 3030310558
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology. 160 pp. Englisch. Seller Inventory # 9783030310554
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Fc Mediated Activity of Antibodies
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Kartoniert / Broschiert. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Examines the structural diversity of the Fc domain for IgG and IgEExplores the role of Fc receptors in the context of infectious, autoimmune, and neoplastic disordersProvides comprehensive information on Fc receptor pathways as an es. Seller Inventory # 448678604
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Fc Mediated Activity of Antibodies : Structural and Functional Diversity
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ISBN 10: 3030310558
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Taschenbuch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology. Seller Inventory # 9783030310554
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Fc Mediated Activity of Antibodies: Structural and Functional Diversity (Current Topics in Microbiology and Immunology)
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Taschenbuch. Condition: Neu. Neuware -This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 160 pp. Englisch. Seller Inventory # 9783030310554
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