Germ Cells (Subject Collections from Cold Spring Harbor Perspectives in Biology) - Hardcover

Paolo Sassone-Corsi; Margaret T. Fuller; Robert Braun

 
9781936113514: Germ Cells (Subject Collections from Cold Spring Harbor Perspectives in Biology)
Hardcover
ISBN 10: 1936113511 ISBN 13: 9781936113514
Publisher: Cold Spring Harbor Press, 2011

Synopsis

In sexually reproducing organisms, germ cells give rise to gametes and serve as the link between generations. A key event during germ cell development is the decision to leave mitosis and enter meiosis, leading to the formation of mature eggs and sperm. Germ cell development involves unique gene expression programs and the establishment of epigenetic marks that ensure success during fertilization and embryo development. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Biology reviews the biology of germ cells in metazoans. The contributors describe the undifferentiated state of germline stem cells, the triggers for meiotic entry, and the transcriptional and post transcriptional controls during spermatogenesis and oogenesis that lead to the formation of mature gametes. The expression of sex linked genes and the establishment of genomic imprinting in the germline are also covered. This volume, which includes discussions of gamete recognition proteins, egg activation, and genetic reprogramming following nuclear transfer, is an indispensable reference for cell, molecular, and developmental biologists and anyone wishing to understand the implications of germ cell biology for reproductive technologies.

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Publisher
Cold Spring Harbor Press
Publication date
2011
Language
English
ISBN 10 
1936113511
ISBN 13 
9781936113514
Binding
Hardcover
Edition number
1
Number of pages
300
Editor
Paolo Sassone-Corsi, Margaret T. Fuller, Robert Braun