Bioinformatics: Methods Express is unique. It is a book on bioinformatics that makes sense to non-bioinformaticians. Bioinformatics: Methods Express helps you answer common questions such as: *what else is similar to my gene?; *does this protein have any transmembrane regions?; *how do I visualize an alignment between these DNAs?; *where can I find specific transcription factor sequences? The book provides the clear advice and explicit protocols that non-bioinformaticians need in order to understand what to do - and how to avoid common pitfalls. Each chapter guides you through the major databases and tools with worked examples - all accompanied by sample data files available online. Topics covered include: *data access; *sequence searches and alignments; *identification and annotation of features; *the transcriptome; *protein structure and function; *comparisons and phylogeny. Bioinformatics: Methods Express is a comprehensive manual for all wet-bench scientists who need to use bioinformatics - from postgraduate student to principal investigator. www.scionpublishing.com/bioinformatics contains comprehensive datasets which allow the reader to practise the techniques described in the book. Contents INTRODUCTION (Paul H. Dear); 1. Database resources for wet-bench scientists (Neil Hall and Lynn Schriml); 2. Navigating sequenced genomes (Melody Clark and Thomas Schlitt); 3. Sequence similarity searches (Jaap Heringa and Walter Pirovano); 4. Gene prediction (Marie-Adele Rajandream); 5. Prediction of non coding transcripts (Alex Bateman and Sam Griffiths-Jones); 6. Finding regulatory elements in DNA sequence (Debraj GuhaThakurta and Gary Stormo); 7. Expressed sequence tags (Arthur Gruber); 8. Protein structure, classification and prediction (Arthur Lesk); 9. Gene ontology (Vineet Sangar); 10. Prediction of protein function (Rodrigo Lopez); 11. Multiple sequence alignment (Burkhard Morgenstern); 12. Inferring phylogenetic relationships from sequence data (Peter Foster); Appendix; Index. Note from the Publisher: The following titles in the Methods Express series may also be of interest: Biosensors, Cell Imaging, DNA Microarrays, Expression Systems, Immunohistochemistry, PCR, Proteomics, and Whole Genome Amplification.
"synopsis" may belong to another edition of this title.
This title is part of Scion's Methods Express series: a series
of books written for busy life science researchers. Each book provides:
protocols in step-by-step detail; comprehensive troubleshooting; example
data as benchmarks; key references and further reading.
Books in the series include:
Bioinformatics (190484216X), Biosensors (1904842127), Cell Imaging
(1904842046), DNA Microarrays (1904842151), Immunohistochemistry
(1904842038), PCR (1904842283), Proteomics (1904842135), Whole Genome
Amplification (1904842070)
"Bioinformatics: Methods Express" is unique. It is a book on bioinformatics that makes sense to non-bioinformaticians. It allows researchers who are not bioinformatics specialists to find answers to fundamental bioinformatics questions which they need to pursue their work successfully. It couples accessible theoretical background information with the explicit protocols that non-bioinformaticians need in order to understand what to do - and how to avoid common pitfalls. "Bioinformatics: Methods Express" is a comprehensive but readily-accessible research guide; every chapter discusses the merits and limitations of various bioinformatics approaches and then provides clear advice and unambiguous protocols. It is an essential companion for all researchers, from PhD student to Principal Investigator, whose work can benefit from a bioinformatics approach.
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