Plasmids: Current Research and Future Trends - Hardcover

Hardcover

ISBN 10: 1904455352 ISBN 13: 9781904455356

Publisher: Caister Academic Press, 2008

Synopsis

Plasmids are fascinating entities which can replicate autonomously in bacterial, archaeal, and eukaryotic cells. They profit from the cellular environment of the host but can also carry a rich diversity of genes which can be beneficial for the host. Plasmids confer the ability to degrade organic compounds and to fix nitrogen. In addition, plasmids carry antibiotic resistance genes and their spread in pathogenic bacteria is of great medical importance. Plasmids are used in molecular studies of various organisms with ramifications in synthetic biology, medicine, ecology, and evolution, as well as basic research in molecular and structural biology. Written by acknowledged experts in the field, this volume provides an up-to-date treatment of the structure, function, and application of plasmids, with a particular emphasis on current and future trends. The book is aimed primarily at research scientists, graduate students, and professional scientists, but will also be of great interest to all molecular biologists and microbiologists involved in research or teaching. Chapters include a historical perspective on E. coli plasmids and the scientific background of the plasmids used routinely in laboratories to clone genes and to express proteins, an overview on the plasmids of archaea and eukarya, bioinformatic tools, horizontal gene transfer, and the process of DNA transfer. Two entire chapters are devoted to the important medical applications of plasmids, including the correction of gene defects and vaccines to treat cancer or infectious diseases. This essential book is for all molecular biology laboratories.

About this title

Synopsis

Lipps (biochemistry, U. of Bayreuth, Germany) presents eight survey papers reviewing various areas in the research of plasmids (extra-chromosomal DNA molecules capable of replicating independently of chromosomal DNA), which he notes presents a "field of research with ramification in synthetic biology, medicine, ecology and evolution as well as basi

Edition details

• Publisher: Caister Academic Press
• Publication date: 2008
• Language: English
• ISBN 10: 1904455352
• ISBN 13: 9781904455356
• Binding: Hardcover
• Number of pages: 272
• Editor: Lipps Georg