Molecular Genetics Of Early Hu - Softcover

Strachan, Tom

Softcover

ISBN 10: 1859960316 ISBN 13: 9781859960318

Publisher: Garland Science, 1997

Synopsis

Aimed at all researchers into human development and the wider medical research audience, this text brings together various strands of the discipline of the molecular genetics of early human development, and provides examples of the approaches being used. Human development disorders are a significant clinical burden and should ideally be investigated by the study of normal human embryos. However, the studies have been hampered by the lack of material and by public sensitivities. Much reliance has been placed on extrapolating data from mouse embryos, but there is an increased awareness of fundamental differences between the mouse and human genomes.

About this title

From the Back Cover

* The first book to provide a comprehensive review of the new molecular genetic approaches to studies of early human development
* Covers the broader issues of clinical relevance, ethics, biological studies and historical background
* Essential for researchers in development and compelling reading for anyone interested in the future of embryonic research and human testing
Human developmental disorders are a significant clinical burden and a focus of intensive research. Traditionally, mouse embryos have been used to model patterns of early human development. However, there is increasing evidence to show that early human and mouse development are substantially different, both at the anatomical level and at the level of gene expression. This means that the mouse is limiting as a model of human development and has necessitated a new direction in the path of developmental research with more emphasis on molecular genetical approaches in humans.
This book is the first to review the new and exciting genetic approach to the study of early human development. The novel research is discussed by leading scientists in the field. These approaches are then put into perspective with a summary of clinical relevance, ethical issues, historical background, anatomical and other biological studies, and the continuing importance of mouse studies. The book is essential reading for researchers in development, and the broader issues will appeal to a wider audience, including clinicians and molecular geneticists.

Edition details

• Publisher: Garland Science
• Publication date: 1997
• Language: English
• ISBN 10: 1859960316
• ISBN 13: 9781859960318
• Binding: Paperback
• Edition number: 1
• Number of pages: 280