In these proceedings from the July 2004 symposium, contributors describe their research in the endocytosis and exocytosis of proteins and lipids, especially on the functions of lipids and rafts and clathrin-coated vesicles. They also describe work on the role of lipids and rafts in cell signaling and in disease. Topics of the 21 papers include the role of microtubules in transport, kinases-regulating Golgi apparatus structure and functions, N-glycans as apical targeting signals, aspects of dominant distal renal tubular acidosis, regulation of clathrin-coated vesicles and imaging of clathrin-based endocytosism, membrane traffic to and from lysosomes, lipid rafts in protein interaction and signaling, the role of brain cholesterol in Alzheimer's Disease, endocytosis and retrograde axonal traffic in motor neurons, the biophysics and sociology of ceramides, reversible electrostatic interactions and BAR domains and membrane curvature. Annotation ©2004 Book News, Inc., Portland, OR (booknews.com)
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"Lipids, Rafts and Traffic" is the published proceedings of the Biochemical Society's Annual Symposium held at BioScience2004 in July 2004. The book describes the endocytosis and exocytosis of proteins and lipids, focusing on the role and mechanism of action of lipid rafts and clathrin-coated vesicles in these processes. The role of lipids and rafts in cell signalling and in disease states is also described.
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