Surfaces and Interfaces for Biomaterials (Woodhead Publishing Series in Biomaterials) - Hardcover

P. Vadgama

Hardcover

ISBN 10: 1855739305 ISBN 13: 9781855739307

Publisher: Woodhead Publishing Ltd, 2005

Synopsis

This book presents our current level of understanding on the nature of a biomaterial surface, the adaptive response of the biomatrix to that surface, techniques used to modify biocompatibility, and state-of-the-art characterisation techniques to follow the interfacial events at that surface.

Key Features: complete coverage on the fundamentals of surface structure and forming to biological and clinical outcomes; includes reviews of key surface analytical techniques; edited by a renowned expert and written by an international team of authors.

Contents: Part 1 Forming methods: Fundamental properties of surfaces; Control of polymeric biomaterial surfaces; Organic thin film architectures: fabrication and properties; Membranes and permeable films; Stable use of biosensors at the sample interface; Micro- and nanoscale surface patterning techniques for localising biomolecules and cells: the essence of nanobiotechnology. Part 2 Measurement, monitoring and characterisation: Surface spectroscopies; Surface microscopies; Nanoidentation; Surface plasmon resonance; Ellipsometry for optical surface study applications; Neutron reflection; Microgravimetry. Part 3 Surface interactions and in-vitro studies: Interaction between biomaterials and cell tissues; Blood flow dynamics and surface interactions; Cell guidance through surface cues; Controlled cell deposition techniques; Biofouling in membrane separation systems. Part 4 Surface interactions and in-vivo studies: Bioactive 3D scaffolds in regenerative medicine: the role of interface interactions; Intravascular drug delivery systems and devices: interactions at biointerface; Surface degradation and microenvironmental outcomes; Microbial biofilms and clinical implants; Extracellular matrix molecules in vascular tissue engineering; Biomineralisation processes; On the topographical characterisation of biomaterial surfaces. Part 5 Appendices: Surface modification of polymers to enhance biocompatibility; Issues concerning the use of assays of cell adhesion to biomaterials; Protein adsorption to surfaces and interfaces.

About this title

About the Author

P Vadgama is Director of the Interdisciplinary Research Centre in Biomedical Materials at Queen Mary, University of London.

From the Back Cover

Given such problems as rejection, the interface between an
implant and its human host is a critical area in biomaterials. Surfaces and
interfaces for biomaterials summarises the wealth of research on
understanding the surface properties of biomaterials and the way they
interact with human tissue.

The first part of the book reviews the way biomaterial surfaces form. Part
Two discusses ways of monitoring and characterising surface structure and
behaviour. The final two parts of the book look at a range of in vitro and
in vivo studies of the complex interactions between biomaterials and the
body. Chapters cover such topics as bone and tissue regeneration, the role
of interface interactions in biodegradable biomaterials, microbial biofilm
formation, vascular tissue engineering and ways of modifying biomaterial
surfaces to improve biocompatibility.

Surfaces and interfaces for biomaterials is a standard work on how to
understand and control surface processes in ensuring biomaterials are used
successfully in medicine.

Edition details

• Publisher: Woodhead Publishing Ltd
• Publication date: 2005
• Language: English
• ISBN 10: 1855739305
• ISBN 13: 9781855739307
• Binding: Hardcover
• Number of pages: 824
• Editor: P. Vadgama