Sterilisation of Tissues Using Ionising Radiation (Woodhead Publishing Series in Biomaterials) - Hardcover

J.F. Kennedy

Hardcover

ISBN 10: 1855738384 ISBN 13: 9781855738386

Publisher: Woodhead Publishing Ltd, 2005

Synopsis

This volume contains the proceedings of the Cellucon Trust/International Atomic Energy Agency meeting on the use of ionising radiation for tissue sterilisation held at the North East Wales Institute, September 2003. Existing methods and processing for sterilising tissues are proving, in many instances inadequate. Infections have been transmitted from the graft to the recipient, and attention has now been drawn to the need for a reliable end sterilisation method which does not damage the functionality of the final tissue. This volume identifies the best method of using radiation technology to assist in the production of safe tissue allografts. Tissue bankers, users of tissues for transplantation and regulators who oversee safety will all find this book an invaluable source of reference.

Key Features: high-quality papers highlighting the most recent developments in this important area; includes the full code of practice for the radiation sterilisation of tissues; edited by a highly respected team of experts.

Contents: Part 1 Standards for tissue banks and for radiation sterilisation of tissues. Part 2 Methodology in the sterilisation and preservation of tissues. Part 3 Effect of radiation on bone, tissues and their components. Part 4 Viral aspects of tissue for transplantation. Part 5 Microbiological aspects of tissue for transplantation.

About this title

About the Author

John F Kennedy is a director of Birmingham Carbohydrate and Protein Technology Group, University of Birmingham Glyn O Phillips is the chairman of Research Transfer Ltd Peter A Williams is a director of the Centre for Water Soluble Polymers.

From the Back Cover

Existing methods and processing for sterilising tissues are
proving inadequate in many instances. Infections have been transmitted from
the graft to the recipient and in the USA the Centre for Disease Control
and other regulatory bodies have drawn attention to the need for a reliable
end sterilisation method which does not damage the functionality of the
final tissue. Safety of surgical allografts is, therefore, a major concern
due to microbial and viral contamination of tissues which is now a problem
even in the most sophisticated centres.

The Presidents of the main Professional Association of Tissue Banks;
American, European and Latin American met in Vienna to review the situation
and concluded that the time was opportune to organise an international high
level expert meeting, which would identify the best method of using
radiation technology to assist in the production of safe tissue allografts

Sterilisation of biological tissues with ionising radiations provides the
information on this subject presented at an international meeting in Wales,
supported by the International Atomic Energy Agency. New methods of
protecting the tissues were presented which at the same time allow the use
of sufficiently high doses of ionising radiations to inactivate invading
organisms. A Code of Practice for the Radiation Sterilisation of Tissues
was evaluated and the outcome and the full Code is included in this volume,
as well as explorations of all of the methodologies used in the field.

Sterilisation of biological tissues with ionising radiations is the only
volume of its kind and as such is an invaluable source of information for
those working in tissue banks, transplant surgeons and the safety
regulators.

Edition details

• Publisher: Woodhead Publishing Ltd
• Publication date: 2005
• Language: English
• ISBN 10: 1855738384
• ISBN 13: 9781855738386
• Binding: Hardcover
• Number of pages: 352
• Editor: J.F. Kennedy, Glyn O. Phillips, P.A. Williams