This volume is a scholarly reference to published research results on the neurobiology and neuroanatomy of depression and the association of depression with disorders of the central nervous system. The book reviews and discusses aspects of recent research on the underlying mechanisms of depression, including neurotransmitter dysregulation, hypothalamus-pituitary-adrenal axis abnormalities, and cellular resistance. Illustrated with tables, graphs, and charts, Depression and Brain Dysfunction is the first book to include the recent advances in functional neuroimaging of the structural and anatomical defects in patients with significant symptoms of depression.
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In recent years, strong evidence has emerged through numerous independent studies that clinical depression is frequently co-existent with many neurologic disorders, including Parkinson's disease, multiple sclerosis, Alzheimer's, and in particular, epilepsy. "Depression and Brain Dysfunction" provides a scholarly reference to the published research results related to the neurobiology and neuroanatomy of depression, and the association of depression with disorders of the central nervous system. The first book to cover the recent advances in functional neuroimaging of the structural and anatomical defects in people with significant symptoms of depression, this important text also includes: * reviews and discussions of aspects of recent research on the underlying mechanisms of depression, including neurotransmitter dysregulation, hypothalamus-pituitary-adrenal axis abnormalities, and cellular resistance * an exploration of the epidemiology, underlying neurobiology, neuroimaging findings, health outcomes and treatment considerations of depression in major neurological disorders, as well as the implications for management.
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