Synopsis
"Metastasis is a critical stage in cancer progression in which cells from the original tumor spread to other locations in the body and seed secondary tumors. This volume examines the molecular mechanisms underlying metastasis, describing how malignant cells change morphology, migrate out of the primary site, and establish new tumors at distant locations. It also discusses ongoing research into how this may be prevented"--
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Search results for Metastasis: Mechanism to Therapy (Perspectives Cshl)
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Metastasis : Mechanism to Therapy
Published by
Cold Spring Harbor Laboratory Press, 2019
ISBN 10: 1621823245
ISBN 13: 9781621823247
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Seller: GreatBookPrices, Columbia, MD, U.S.A.
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Metastasis : Mechanism to Therapy
Published by
Cold Spring Harbor Laboratory Press, 2019
ISBN 10: 1621823245
ISBN 13: 9781621823247
New
Hardcover
Seller: GreatBookPrices, Columbia, MD, U.S.A.
Seller rating 5 out of 5 stars
Condition: New. Seller Inventory # 37630682-n
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Metastasis: Mechanism to Therapy (Hardcover)
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Cold Spring Harbor Laboratory Press,U.S., New York, 2019
ISBN 10: 1621823245
ISBN 13: 9781621823247
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Hardcover
Seller: Grand Eagle Retail, Bensenville, IL, U.S.A.
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Hardcover. Condition: new. Hardcover. Nearly all types of cancer have the ability to metastasize, or spread from one organ or tissue in the body to another. Metastatic disease is responsible for the majority of cancer deaths and, therefore, is a critical area of research. Work to better understand the metastatic cascade-how cells detach from a primary tumor, migrate through the body, and seed secondary tumors at distant locations-will lead to improved treatment options for patients with cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the recent progress that has been made in understanding the molecular mechanisms underlying metastasis and how this knowledge is paving the way for new therapeutic targets. The contributors discuss progress in defining mutations that might be driving metastasis, the formation of a premetastatic niche and how it enhances the establishment of a secondary tumor, and how changes that occur during aging increase the metastatic capacity of tumor cells. They also consider the selection and colonization of common target organs (e.g., brain, liver, and bones) during metastasis and the roles of immune cells and extracellular vesicles at different steps of the metastatic cascade. Cellular plasticity-including evidence for metastatic stem cells and the role of tumor cell dormancy in recurrent metastasis-is also covered. In addition, the authors describe the development of in vivo models and techniques for studying metastasis, methods for monitoring tumor progression and metastatic spread (e.g., intravital microscopy and liquid biopsy), and immunotherapies that can potentially target cancer metastasis. This volume is therefore a vital reference for all cancer biologists and clinician-scientists concerned with defeating cancer. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. Seller Inventory # 9781621823247
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Metastasis: Mechanism to Therapy
Published by
Cold Spring Harbor Laboratory Press,U.S., US, 2019
ISBN 10: 1621823245
ISBN 13: 9781621823247
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Hardback. Condition: New. Seller Inventory # LU-9781621823247
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Metastasis: Mechanism to Therapy
Published by
Cold Spring Harbor Laboratory Pr, 2019
ISBN 10: 1621823245
ISBN 13: 9781621823247
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Hardcover
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Hardcover. Condition: Brand New. 325 pages. 10.25x7.25x1.00 inches. In Stock. Seller Inventory # x-1621823245
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Metastasis
Published by
COLD SPRING HARBOR LABORATORY, 2019
ISBN 10: 1621823245
ISBN 13: 9781621823247
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Seller: moluna, Greven, Germany
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Metastasis: Mechanism to Therapy
Published by
Cold Spring Harbor Laboratory Press,U.S., US, 2019
ISBN 10: 1621823245
ISBN 13: 9781621823247
New
Hardcover
Seller: Rarewaves USA United, OSWEGO, IL, U.S.A.
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Hardback. Condition: New. Seller Inventory # LU-9781621823247
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Metastasis: Mechanism to Therapy
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Cold Spring Harbor Laboratory Press Dez 2019, 2019
ISBN 10: 1621823245
ISBN 13: 9781621823247
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Hardcover
Seller: AHA-BUCH GmbH, Einbeck, Germany
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Buch. Condition: Neu. Neuware - Written and edited by experts in the field, this collection covers the recent progress that has been made in understanding the molecular mechanisms underlying metastasis and how this knowledge is paving the way for new therapeutic targets. The contributors discuss progress in defining mutations that might be driving metastasis, the formation of a premetastatic niche and how it enhances the establishment of a secondary tumor, and how changes that occur during aging increase the metastatic capacity of tumor cells. Seller Inventory # 9781621823247