CHITOSAN: Modifications & Applications in Dosage Form Design (Biotechnology in Agriculture, Industry and Medicine) - Softcover

TIWARY A.K.

 
9781617611742: CHITOSAN: Modifications & Applications in Dosage Form Design (Biotechnology in Agriculture, Industry and Medicine)
Softcover
ISBN 10: 1617611743 ISBN 13: 9781617611742
Publisher: Gazelle, 2012

Synopsis

Chitosan is the deacetylated form of chitin. Generally, the substance becomes soluble in dilute acids when the degree of deacetylation is more than 50%. The solubility of chitosan in dilute acids is often needed to be modified when specific drug release properties have to be tailored into the dosage form. The available toxicological data on chitosan and its modified forms appears to indicate its safety for oral use because high doses have been found to be tolerated well in rodents and rabbits. However, its local action as a haemostatic together with its ability to activate macrophages and cause cytokine release may require a careful assessment of its safety for parenteral use. This book offers the dynamics of chitosan's detailed composition.

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Publisher
Gazelle
Publication date
2012
Language
English
ISBN 10 
1617611743
ISBN 13 
9781617611742
Binding
Paperback
Number of pages
1