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Forensic and Clinical Applications of Solid Phase Extraction (Forensic Science and Medicine) - Hardcover
Synopsis
Presenting a compendium of methods and supporting data for solid phase extraction of compounds of interest in the field of clinical and forensic toxicology, this volume will help researchers to solve their individual separation problems.
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Review
"... a recommended addition to the laboratory shelf, as a training aid and also as a a convenient source of SPE methodolgical and analytical data." -ASCLD
"This book is detailed, well organized, and is an excellent laboratory reference manual for the application of SPE to forensic or clinical analyses." - Canadian Society of Forensic Science Journal
From the Back Cover
Solid phase extraction (SPE) has become a powerful and extensively used technique in the clean up and concentration of samples for analysis in a wide variety of analytical techniques. In Forensic and Clinical Applications of Solid Phase Extraction, hands-on experts explain the principles behind SPE and provide a host of readily reproducible protocols designed to allow the reader to master his or her extraction challenges with little or no additional help. These detailed methods are particularly suited to solving extraction problems in forensic and clinical chemistry and include readily understandable explanations of such complicated ideas as the principles of pH, ion exchange, and copolymeric mechanism-enhanced SPE. Numerous actual chromatograms, based on original research and from diverse applications, demonstrate the technique and the results that can be achieved. The applications are grouped by drug types and matrices. Extensive appendices allow fast access to frequently needed information on reagents, the preparation of solutions and buffers, milliequivalent and millimode calculations, buffers and pKa for SPE, and a complete RapidTrace® technical manual. Each proven protocol is described in step-by-step detail and contains an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.
State-of-the-art and highly practical, Forensic and Clinical Applications of Solid Phase Extraction is a complete laboratory reference manual that will give forensic and clinical chemists at any level of expertise the ability to make clean extractions with high recoveries and effectively enhance their analytical problem-solving skills.
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