Biomedical Surfaces (Engineering in Medicine & Biology) - Hardcover

Jeremy Ramsden

Hardcover

ISBN 10: 1596932406 ISBN 13: 9781596932401

Publisher: Artech House, 2008

Synopsis

The success of artificial joints and other implants is greatly influenced by the constant interactions that take place between implant surfaces and living tissues. This first-of-its-kind design resource explores the processes and surface modifications that occur in bio/non-bio interfaces, and offers biomedical engineers state-of-the-art design, materials selection, and manufacturing guidance including nanotechnology breakthroughs that are ushering in a new era of implant capabilities. This book discusses biomedical surface attributes and addresses design issues involving materials in contact with biofluids, as in heart valves and dialysis machines. Professionals find details on implant lubrication and wear issues. The book also discusses how to predict biomaterial interactions with body tissues.

About this title

About the Author

Jeremy Ramsden is a professor of nanotechnology in the Materials Department of Cranfield University, United Kingdom. He has published over 100 research articles covering topics in adsorption and desorption, biological macromolecules, and self-assembly and organizing processes at the nanoscale, and has chaired several international conferences devoted to biomolecular interactions. He is editor-in-chief of the Journal of Biological Physics and Chemistry, and founder of the MEMOCS research consortium uniting a dozen academic research groups and industrial firms in developing integrated-optical membrane-based sensors for medical and environmental applications. Dr. Ramsden studied Natural Sciences at Cambridge University and received his Ph.D. from the Institute of Chemical Physics, Swiss Federal Institute of Technology in Lausanne.

From the Inside Flap

Introduction--Definition of Biomaterials. The Role of Surfaces in Governing Biomaterial Performance. Modifications to Surfaces in Contact with Biological Media (Biofluids, Tissues, Cells).

The Adsorption of Biomacromolecules--Physical--Chemical Fundamentals.

Haemocompatibility--Processes in Which Biomaterials Are in Contact with Biofluids. Stents. Heart Valves. Dialysis Machines. Design Issues Involving Suppression of Biomacromolecule Absorption or Selective Adsorption.

Lubrication--Materials Acting as Lubricants Between Solid Surfaces. Tribology of the Surfaces. Wear Issues. Particle Release from Prostheses. Mechanical Fatigue.

Cells and Tissues--Biocompatibility with Hard and Soft Tissues. Protein Adsorption and Desorption. Information Flow Between Surface and Cell. Immune Cell Response and Behavior. Assimilation Issues. Infection Risks.

Drug Delivery Surfaces--General Properties of Nano- and Microporous Drug Delivery Materials. Percolation Theory. Interactions of Drug Delivery Particles and Biological Media.

Prospects for Smart and Nano Materials--Smart Surfaces. Interactions Between Cells/Tissues and Adaptive Nano Materials.

Edition details

• Publisher: Artech House
• Publication date: 2008
• Language: English
• ISBN 10: 1596932406
• ISBN 13: 9781596932401
• Binding: Hardcover
• Number of pages: 242