Immunoinformatics: Predicting Immunogenicity In Silico: 409 (Methods in Molecular Biology, 409) - Hardcover

 
9781588296993: Immunoinformatics: Predicting Immunogenicity In Silico: 409 (Methods in Molecular Biology, 409)

Synopsis

Immunoinformatics: Predicting Immunogenicity In Silico is a primer for researchers interested in this emerging and exciting technology and provides examples in the major areas within the field of immunoinformatics. This volume both engages the reader and provides a sound foundation for the use of immunoinformatics techniques in immunology and vaccinology.

The volume is conveniently divided into four sections. The first section, Databases, details various immunoinformatic databases, including IMGT/HLA, IPD, and SYEPEITHI. In the second section, Defining HLA Supertypes, authors discuss supertypes of GRID/CPCA and hierarchical clustering methods, Hla-Ad supertypes, MHC supertypes, and Class I Hla Alleles. The third section, Predicting Peptide-MCH Binding, includes discussions of MCH binders, T-Cell epitopes, Class I and II Mouse Major Histocompatibility, and HLA-peptide binding. Within the fourth section, Predicting Other Properties of Immune Systems, investigators outline TAP binding, B-cell epitopes, MHC similarities, and predicting virulence factors of immunological interest.

Immunoinformatics: Predicting Immunogenicity In Silico merges skill sets of the lab-based and the computer-based science professional into one easy-to-use, insightful volume.

"synopsis" may belong to another edition of this title.

Review

"Investigators considering problems of recombinant vaccine design, possible host responses, and how to select likely sites from a large pool of information (the protein of interest) will find valuable material here." -Doody's Book Review, Weighted Numerical Score:77 - 3 Stars

"...a value to virtually any investigator in this general field." -Doody's Book Review, Weighted Numerical Score:77 - 3 Stars

 

"...a valuable addition to libraries in universities and research institutes, R & D firms engaged in the development of vaccines and immunotherapeutics, and clinical research centres." -Immunology news

Synopsis

Immunoinformatics is the application of informatics techniques drawn from computer science to molecules of the immune system and their interactions. This work is presented by editor Flower (The Jenner Institute, U. of Oxford, UK) as a primer on this new technology and its application to the computational prediction of immunogenicity, the ability to

"About this title" may belong to another edition of this title.

Other Popular Editions of the Same Title

9781617377259: Immunoinformatics: Predicting Immunogenicity In Silico: 409 (Methods in Molecular Biology, 409)

Featured Edition

ISBN 10:  1617377252 ISBN 13:  9781617377259
Publisher: Humana, 2010
Softcover