Anticoagulants, Antiplatelets, and Thrombolytics: Methods and Protocols: v. 93 (Methods in Molecular Biology) - Hardcover

Hardcover

ISBN 10: 1588290832 ISBN 13: 9781588290830

Publisher: Humana Press Inc., 2003

Synopsis

This collection of review articles highlights the latest development of antithrombotics and provides proven experimental methods for the further development of new and improved anticoagulants. Among the cutting-edge developments reviewed are the novel usage of low molecular weight heparins, such antithrombin agents as the hirudin, and such antiplatelet drugs as the GPIIb/IIIa inhibitors and ADP receptor antagonists. Additional innovations discussed include aspirin and clopidogrel, the expanded use of polytherapeutic approaches, antiproteases (factors IIa, Xa, and VIIa), tissue factor targeting, platelet receptor targeting, and antithrombin III modulation.

About this title

Review

From the reviews:

"This book contains a number of informative topics on the latest advances in the field. ??? Basic science is completed with clinical results. Very complete guidelines for treatment of deep thrombosis and pulmonary embolism ends the book. This recommendable book ??? provides a clinical audience with a complete update on a major field in medicine." (Michel Telerman, Acta Cardiologica, April, 2005)

From the reviews:

"This book contains a number of informative topics on the latest advances in the field. a ] Basic science is completed with clinical results. Very complete guidelines for treatment of deep thrombosis and pulmonary embolism ends the book. This recommendable book a ] provides a clinical audience with a complete update on a major field in medicine." (Michel Telerman, Acta Cardiologica, April, 2005)

From the Back Cover

During the past decade, remarkable progress has been made in the development of newer drugs to prevent and treat thromboembolic disorders, such as oral direct anti-Xa and anti-IIa antagonists, as well as oral antiplatelet ADP antagonists with rapid onset and offset. In addition, there has been concentrated effort aimed at identifying novel uses of traditional antithrombotic drugs, such as aspirin, heparin, and oral anticoagulants, as well as combinations of agents, such as more than one antiplatelet, antiplatelet with anticoagulant, antiplatelet with or without thrombolytic. Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition provides updates on various strategies in thrombosis, experimental models, and clinical and recent advances in the discovery and development of novel antithrombotics. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Easy to use and up to date, Anticoagulants, Antiplatelets, and Thrombolytics, Second Edition is an ideal guide for researchers aiming for the future of this vital field, focusing on the prevention of thromboembolic disorders and the protection of the vascular endothelium.

Edition details

• Publisher: Humana Press Inc.
• Publication date: 2003
• Language: English
• ISBN 10: 1588290832
• ISBN 13: 9781588290830
• Binding: Hardcover
• Number of pages: 320
• Editor: Mousa Shaker A.