Translational Medicine: Strategies and Statistical Methods: 28 (Chapman & Hall/CRC Biostatistics) - Hardcover

Hardcover

ISBN 10: 1584888725 ISBN 13: 9781584888727

Publisher: Chapman and Hall/CRC, 2008

Synopsis

Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing. As a result, translational medicine (TM) is becoming increasingly important in the healthcare industry – a means of maximizing the consideration and use of information collected as compounds transition from initial lab discovery, through pre-clinical testing, early clinical trials, and late confirmatory studies that lead to regulatory approval of drug release to patients.

Translational Medicine: Strategies and Statistical Methods suggests a process for transitioning from the initial lab discovery to the patient’s bedside with minimal disconnect and offers a comprehensive review of statistical design and methodology commonly employed in this bench-to-bedside research.

Documents Alternative Research Approaches for Faster and More Accurate Data Judgment CallsElaborating on how to introduce TM into clinical studies, this authoritative work presents a keen approach to building, executing, and validating statistical models that consider data from various phases of development. It also delineates a truly translational example to help bolster understanding of discussed concepts.

This comprehensive guide effectively demonstrates how to overcome obstacles related to successful TM practice. It contains invaluable information for pharmaceutical scientists, research executives, clinicians, and biostatisticians looking to expedite successful implementation of this important process.

About this title

About the Author

Dennis Cosmatos, Shein-Chung Chow

Edition details

• Publisher: Chapman and Hall/CRC
• Publication date: 2008
• Language: English
• ISBN 10: 1584888725
• ISBN 13: 9781584888727
• Binding: Hardcover
• Edition number: 1
• Number of pages: 242
• Editor: Cosmatos Dennis, Chow Shein-Chung