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Synopsis
Building upon the pioneering work of Klaus Weber, who in the 1970s discovered a key to the malignant transformation of normal cells by tumor virus infection or mutations via the disruption of actin cables and subsequent induction of membrane ruffling occurring with oncogenes such as v-Ras and v-Src, the global contributors aim toward the quantum leap of creating an anticancer Holy Grail that would attenuate the malignant activity of oncogenic mutants. The two dozen papers are organized under the four major headings of: actin-cytoskeleton, Ras/Rho family GTPases, links between G proteins and actin, and new anticancer drugs (e.g. farnesyltransferase inhibitors, SCH51344, and azatyrosine). Annotation c. by Book News, Inc., Portland, Or.
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Synopsis
This text examines the role of G protein-mediated signal transduction and the cytoskeleton in carcinogenesis.
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G Proteins, Cytoskeleton, and Cancer
Seller: Ammareal, Morangis, France
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Hardcover. Condition: Très bon. Ancien livre de bibliothèque. Edition 1998. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Very good. Former library book. Edition 1998. Ammareal gives back up to 15% of this item's net price to charity organizations. Seller Inventory # E-984-242
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G Proteins, Cytoskeleton and Cancer (Molecular Biology Intelligence Unit)
Seller: Revaluation Books, Exeter, United Kingdom
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Hardcover. Condition: Brand New. 1st edition. 377 pages. 9.20x6.10x1.20 inches. In Stock. Seller Inventory # 1570595518
Quantity: 1 available