This volume examines the various aspects of post-transcriptional RNA processing, including biosynthetic, genetic, and functional aspects of nucleoside modification and editing by nucleoside conversion as well as by nucleoside insertion/deletion. Written by leading researchers in the field, it includes descriptions of the different types of modification/editing, identification of the correspondending enzymes, discussion of cis- and trans- acting sequences, machineries, mechanisms, cellular locations, the biological role of individual modified/edited bases, involvement in diseases like cancer and AIDS, and possible evolutionaly connections between different processes. Modification and Editing of RNA is a valuable reference for researchers, teachers and students, and will be a useful tool for the planning of future research to solve many questions that remain.
This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
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This volume examines the various aspects of post–transcriptional RNA processing, including biosynthetic, genetic, and functional aspects of nucleotide modification and editing by nucleotide conversion as well as by nucleotide insertion/deletion. It covers techniques for identification and localization of modified nucleosides in RNA and chemical synthesis of RNA with site specific incorporation of natural and/or synthetic modified nucleosides.
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