Optimization in Drug Discovery: In Vitro Methods (Methods in Pharmacology and Toxicology) - Softcover
Synopsis
Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve “drug-like” characteristics in addition to efficacy properties and good safety profiles of drug candidates.
Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down the difficult path to successful drug discovery and development.
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From the Back Cover
Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve “drug-like” characteristics in addition to efficacy properties and good safety profiles of drug candidates.
Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down the difficult path to successful drug discovery and development.
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Optimization in Drug Discovery: In Vitro Methods (eng)
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Optimization in Drug Discovery: In Vitro Methods (Methods in Pharmacology and Toxicology)
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Optimization in Drug Discovery : In Vitro Methods
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Optimization in Drug Discovery
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Provides updated variations on assays as well as numerous new protocols for drug discovery optimizationFeatures readily reproducible methods and protocols that are lab-tested and successfulIncludes expert tips and key implementation advice. Seller Inventory # 447957038
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Optimization in Drug Discovery
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thoroughly revised and updated, Optimization in Drug Discovery: In Vitro Methods, Second Edition presents a wide spectrum of in vitro assays including formulation, plasma binding, absorption and permeability, cytochrome P450 (CYP) and UDP-glucuronosyltransferases (UGT) metabolism, CYP inhibition and induction, drug transporters, drug-drug interactions via assessment of reactive metabolites, genotoxicity, and chemical and photo-mutagenicity assays. Written for the Methods in Pharmacology and Toxicology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls. Expert authors have developed and utilized these in vitro assays to achieve 'drug-like' characteristics in addition to efficacy properties and good safety profiles of drug candidates.Comprehensive and up-to-date, Optimization in Drug Discovery: In Vitro Methods, Second Edition aims to guide researchers down the difficult path to successful drug discovery and development. 616 pp. Englisch. Seller Inventory # 9781493960705
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Optimization in Drug Discovery: In Vitro Methods (Methods in Pharmacology and Toxicology)
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Optimization in Drug Discovery: In Vitro Methods (Methods in Pharmacology and Toxicology)
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Optimization in Drug Discovery
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Condition: New. This fresh edition features new assay variations and the latest protocols for optimizing drug discovery. With expert tips and troubleshooting advice, and revised throughout for this second edition, it covers cutting-edge techniques such as cytochrome P450. Editor(s): Caldwell, Gary W.; Yan, Zhengyin. Series: Methods in Pharmacology and Toxicology. Num Pages: 614 pages, 64 black & white illustrations, 49 colour illustrations, 104 black & white tables, biogra. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 31. Weight in Grams: 1156. . 2016. 2 Rev ed. Paperback. . . . . Seller Inventory # V9781493960705
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Optimization in Drug Discovery | In Vitro Methods
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Taschenbuch. Condition: Neu. Optimization in Drug Discovery | In Vitro Methods | Zhengyin Yan (u. a.) | Taschenbuch | xvii | Englisch | 2016 | Humana Press | EAN 9781493960705 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. Seller Inventory # 103477310
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Optimization in Drug Discovery: In Vitro Methods (Methods in Pharmacology and Toxicology)
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Condition: New. PRINT ON DEMAND pp. 597. Seller Inventory # 18375007084