Gene Therapy for Neurological Disorders: Methods and Protocols: 1382 (Methods in Molecular Biology, 1382) - Hardcover

Hardcover

ISBN 10: 1493932705 ISBN 13: 9781493932702

Publisher: Humana, 2015

Synopsis

This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene therapy agent?; How will you model the neurodegenerative disorder that you aim to investigate and what are the proven methods to treat these disorders in preclinical models? Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, Gene Therapy for Neurological Disorders: Methods and Protocols, is a compilation of protocols and instructive chapters intended to give researchers, clinicians, and students of all levels, a foundation upon which future gene therapy experiments can be designed.

About this title

About the Author

Fredric P. Manfredsson, Ph.D. Assistant Professor Michigan State University Division of Translational Science & Molecular Medicine Van Andel Institute 333 Bostwick Ave NE Grand Rapids, MI 49503 Tel: 616-234-0968 Fax: 616-234-0990

From the Back Cover

This volume provides a clear and detailed roadmap of how to design and execute a gene therapy experiment in order to obtain consistent results. Chapters in this book disseminate bits of unknown information that are important to consider during the course of experimentation and will answer questions such as: What delivery vehicle do you use?; How will you ensure that your vector retains stability?; What expression system best fits your needs?; What route will you choose to deliver your gene therapy agent?; How will you model the neurodegenerative disorder that you aim to investigate, and what are the proven methods to treat these disorders in preclinical models? Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and thorough, Gene Therapy for Neurological Disorders: Methods and Protocols, is a compilation of protocols and instructive chapters intended to give researchers, clinicians, and students of all levels, a foundation upon which future gene therapy experiments can be designed.

Edition details

• Publisher: Humana
• Publication date: 2015
• Language: English
• ISBN 10: 1493932705
• ISBN 13: 9781493932702
• Binding: Hardcover
• Edition number: 1
• Number of pages: 507
• Editor: Manfredsson Fredric P.